5425-82-1Relevant articles and documents
Microwave assisted synthesis, docking and antimalarial evaluation of hybrid PABA-substituted 1,3,5-triazine derivatives
Adhikari, Nayana,Kashyap, Ankita,Shakya, Anshul,Ghosh, Surajit Kumar,Bhattacharyya, Dibya Ranjan,Bhat, Hans Raj,Singh, Udaya Pratap
, p. 2389 - 2399 (2020/03/24)
A series of novel PABA-substituted 1,3,5-triazine derivatives were developed via microwave assisted synthesis and subsequently tested for antimalarial activity against chloroquine sensitive 3D7 strain of Plasmodium falciparum using chloroquine as standard. Antimalarial screening result showed that synthesized compounds exhibited IC50 in the range of 4.46 to 79.72 μg mL?1. Among the tested compounds, 4c and 4f showed significant antimalarial activity with low binding energies (BE) -172.32 and 160.41 kcal mol?1 via interacting with Arg122 through the involvement of COOH of the phenyl linked to 1,3,5-triazine. In conclusion, these core scaffolds can be used for future antimalarial drug development.
N-ALKYL MELAMINE FORMALDEHYDE CROSS-LINKING AND CURABLE COMPOSITIONS
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Page/Page column 18-19, (2008/06/13)
This invention relates to bis-N-alkyl melamine formaldehyde cross-linking composition or a mixture of bis- and tris-N-alkyl melamine formaldehyde cross-linking composition. This invention also contemplates curable compositions comprising the bis-N-alkyl melamine formaldehyde composition and an active hydrogen-containing material. The invention further encompasses a curable composition comprising a mixture of bis- and tris-N-alkyl melamine formaldehyde compounds and an active hydrogen-containing material.
Herbicidal sulfonamides
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, (2008/06/13)
Herbicidal sulfonamides such as 2-[[[4-(methylamino)-6-(2,2,2-trifluoroethoxy)-1,3,5-triazin-2-yl]aminocarbonyl]aminosulfonyl]benzoic acid, methyl ester are useful as herbicides and plant growth regulants.