5426-90-4 Usage
Description
8-(2-Cyclohexylethyl)-1,3-dimethyl-7H-purine-2,6(1H,3H)-dione is a purine derivative chemical compound that features a cyclohexylethyl group attached to the 8th carbon atom. It is a 1,3-dimethylated purine derivative known for its potent inhibitory effect on the cyclic nucleotide phosphodiesterase enzyme, which is significant in various cellular processes.
Uses
Used in Pharmaceutical Industry:
8-(2-Cyclohexylethyl)-1,3-dimethyl-7H-purine-2,6(1H,3H)-dione is used as a therapeutic agent for the treatment of cardiovascular diseases, asthma, and inflammation due to its ability to inhibit the cyclic nucleotide phosphodiesterase enzyme, which is implicated in these conditions.
Used in Neuroscience Research:
In the field of neuroscience, 8-(2-Cyclohexylethyl)-1,3-dimethyl-7H-purine-2,6(1H,3H)-dione is utilized for studying cognition and memory, given its potential impact on cellular processes related to these functions. Further research is necessary to fully understand its biological activities and applications in this area.
Check Digit Verification of cas no
The CAS Registry Mumber 5426-90-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,2 and 6 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5426-90:
(6*5)+(5*4)+(4*2)+(3*6)+(2*9)+(1*0)=94
94 % 10 = 4
So 5426-90-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N4O2/c1-18-13-12(14(20)19(2)15(18)21)16-11(17-13)9-8-10-6-4-3-5-7-10/h10H,3-9H2,1-2H3,(H,16,17)
5426-90-4Relevant articles and documents
Inhibition of monoamine oxidase by selected phenylalkylcaffeine analogues
Petzer, Anel,Grobler, Paul,Bergh, Jacobus J.,Petzer, Jacobus P.
, p. 677 - 687 (2014/05/06)
Objectives Caffeine represents a useful scaffold for the design of monoamine oxidase (MAO) type B inhibitors. Specifically, substitution on the C8 position yields structures which are high-potency MAO-B inhibitors. To explore the structure-activity relati
