54287-98-8

Basic information

• Product Name: 2-hydroxy-4-((2-methylbut-3-yn-2-yl)oxy)benzaldehyde
• Synonyms: 2-hydroxy-4-((2-methylbut-3-yn-2-yl)oxy)benzaldehyde
• CAS NO: 54287-98-8
• Molecular Weight: 204.225
• Mol File: 54287-98-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-hydroxy-4-((2-methylbut-3-yn-2-yl)oxy)benzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxy-4-((2-methylbut-3-yn-2-yl)oxy)benzaldehyde(54287-98-8)
• EPA Substance Registry System: 2-hydroxy-4-((2-methylbut-3-yn-2-yl)oxy)benzaldehyde(54287-98-8)

Safety Data

• Hazardous Substances Data: 54287-98-8(Hazardous Substances Data)

Upstream product

• 1111-97-3 3-chloro-3-methylbut-1-yne 
• 95-01-2 2,4-Dihydroxybenzaldehyde 

Downstream Products

• 523-59-1 seseline 
• 54287-99-9 5-hydroxy-2,2-dimethyl-2H-chromene-6-carbaldehyde 

Relevant articles and documents

A One-Pot Synthesis of Pyranocoumarins Through Microwave-Promoted Propargyl Claisen Rearrangement/Wittig Olefination

The reaction between propargyl ethers of hydroxybenzaldehydes and the ylide ethyl (triphenylphosphoranylidene)acetate was carried out under microwave irradiation to regioselectively afford angular pyranocoumarins. The chromene and coumarin heterocyclic scaffolds were simultaneously formed in the same synthetic step without changing the reaction conditions. The natural products seselin, braylin, and dipetalolactone were among the products synthesized by this method.

Convenient Two-step Syntheses of Seselin and Angelicin Derivatives

Convenient two-step approaches are described for the syntheses of seselin (3a), seselin and angelicin derivatives (3b-d and 5a-d) from 2,4-dihydrobenzaldehyde (1a) and 2,4-dihydroxyacetophenone (1b) using tandem Claisen rearrangement and Wittig reaction.