54299-50-2 Usage
Description
(E)-1-(2,4-Dihydroxy-3,6-dimethoxy-phenyl)-3-phenyl-propenone, also known as 3,4-dimethoxy-5-hydroxy-beta-phenethyl phenyl ketone, is a flavonoid compound with the molecular formula C17H16O4. It exhibits a variety of biological activities, such as antioxidant, anti-inflammatory, anti-cancer, anti-microbial, and anti-viral properties. This chemical compound has shown potential as an anti-cancer agent, inducing apoptosis in cancer cells and inhibiting tumor growth.
Uses
Used in Pharmaceutical Industry:
(E)-1-(2,4-DIHYDROXY-3,6-DIMETHOXY-PHENYL)-3-PHENYL-PROPENONE is used as an anti-cancer agent for its ability to induce apoptosis in cancer cells and inhibit tumor growth. Its diverse biological activities make it a promising candidate for the development of novel therapeutics.
Used in Nutraceutical Industry:
(E)-1-(2,4-DIHYDROXY-3,6-DIMETHOXY-PHENYL)-3-PHENYL-PROPENONE is used as a nutraceutical ingredient for its antioxidant properties, which can contribute to the treatment and prevention of various diseases.
Used in Cosmetic Industry:
(E)-1-(2,4-DIHYDROXY-3,6-DIMETHOXY-PHENYL)-3-PHENYL-PROPENONE is used as an active ingredient in cosmetics for its anti-inflammatory and anti-aging effects, potentially improving skin health and appearance.
Used in Agricultural Industry:
(E)-1-(2,4-DIHYDROXY-3,6-DIMETHOXY-PHENYL)-3-PHENYL-PROPENONE is used as a bioactive compound in the agricultural industry for its anti-microbial and anti-viral properties, potentially serving as a natural alternative for pest and disease control in crops.
Check Digit Verification of cas no
The CAS Registry Mumber 54299-50-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,2,9 and 9 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 54299-50:
(7*5)+(6*4)+(5*2)+(4*9)+(3*9)+(2*5)+(1*0)=142
142 % 10 = 2
So 54299-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H16O5/c1-21-14-10-13(19)17(22-2)16(20)15(14)12(18)9-8-11-6-4-3-5-7-11/h3-10,19-20H,1-2H3/b9-8+
54299-50-2Relevant articles and documents
Synthesis, evaluation and quantitative structure–activity relationship (QSAR) analysis of Wogonin derivatives as cytotoxic agents
Bian, Jinlei,Li, Tinghan,Weng, Tianwei,Wang, Jubo,Chen, Yu,Li, Zhiyu
supporting information, p. 1012 - 1016 (2017/09/30)
A novel series of 49 wogonin derivatives were synthesized by introducing group at 7-, 8- or B ring of wogonin. The cytotoxic activities against HepG2, A549 and BCG-823 cancer cell lines were also investigated in vitro. Several of them showed obvious cytotoxic activities and compound 3h possessed the highest potency against HepG2, A549, and BCG-823 with IC50 values of 1.07 μM, 1.74 μM and 0.98 μM, respectively. A quantitative structure-activity relationship (QSAR) study of these synthetic derivatives as well as wogonin indicated that high solubility and low octanol/water partition coefficient are favorable, and excessive electrostatic properties and refractivity are unfavorable for the cytotoxic activities of these wogonin derivatives. These findings and results provide a base for further investigations.