5431-37-8

Basic information

• Product Name: N,N-bis(2-nitrophenyl)ethane-1,2-diamine
• CAS NO: 5431-37-8
• Molecular Formula: C₁₄H₁₄N₄O₄
• Molecular Weight: 302.29
• Mol File: 5431-37-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 550.8°Cat760mmHg
• Flash Point: 286.9°C
• Density: 1.419g/cm³
• CAS DataBase Reference: N,N-bis(2-nitrophenyl)ethane-1,2-diamine(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-bis(2-nitrophenyl)ethane-1,2-diamine(5431-37-8)
• EPA Substance Registry System: N,N-bis(2-nitrophenyl)ethane-1,2-diamine(5431-37-8)

Safety Data

• Hazardous Substances Data: 5431-37-8(Hazardous Substances Data)

Upstream product

• 108-86-1 bromobenzene 
• 88-73-3 2-Chloronitrobenzene 
• 107-15-3 ethylenediamine 
• 1493-27-2 ortho-nitrofluorobenzene 
• 577-19-5 2-nitrophenyl bromide 
• 91-23-6 2-Nitroanisole 
• 88-74-4 2-nitro-aniline 
• 106-93-4 ethylene dibromide 
• 127-09-3 sodium acetate 
• 6780-13-8 1,2-ethanediamine monohydrate 
• 64-17-5 ethanol 

Downstream Products

• 728938-28-1 N,N'-dinitro-N,N'-dipicryl-ethylenediamine 
• 16825-43-7 N,N’-bis(2-aminophenyl)-1,2-ethanediamine 
• 767354-67-6 N,N'-bis-(4-bromo-2-nitro-phenyl)-ethylenediamine 
• 123885-72-3 2,2'-(ethane-1,2-diylbis(azanediyl)bis(2,1-phenylene)bis(azaneylylidene)bis(methaneylylidene))diphenol 

Relevant articles and documents

Graphene-oxide/schiff base N2O4 ligand-palladium: A new catalyst for the synthesis of furan derivatives

In this paper, we aimed at synthesizing GO/H2L-Pd nano-composites (graphene-oxide/schiff base N2O4 Ligand-palladium) as a new heterogeneous catalyst. Different analytical techniques were applied in order to analyze the chemical composition and the structure of the catalyst. The findings revealed that GO/H2L-Pd could catalyze synthesis of furan derivatives in one-pot three-component condensation reaction by different aromatic aldehydes, arylamine and acetylenedicarboxylate. The major advantages of this study are the green and mild procedure, easy reaction work-up, short reaction time, high yields, and reusability of the catalyst.

Synthetic and structural investigations of bis(N -alkyl-benzoselenadiazolium) cations

The synthesis, and spectroscopic and structural characterization of bridged dicationic derivatives of benzo-2,1,3-selenadiazoles are reported. The chloride salt of [H4C6NSeN-CH2-CH2-NSeNC6H4/sub

1,4-Diarylpiperazines and analogs as anti-tubercular agents: Synthesis and biological evaluation

Despite progress in modern chemotherapy to combat tuberculosis, the causative pathogen Mycobacterium tuberculosis (M.tb.) is far from eradicated. Bacillary resistance to anti-mycobacterial agents, bacillary persistence and human immunodeficiency virus (HIV) co-infection hamper current drug treatment to completely cure the infection, generating a constant demand for novel drug candidates to tackle these problems. A small library of novel heterocyclic compounds was screened in a rapid luminometric in vitro assay against the laboratory M.tb. strain H37Rv. A group of amidines was found to have the highest potency and was further evaluated for acute toxicity against C3A hepatocytes. Next, the most promising compounds were evaluated for activity against a multi-drug resistant clinical isolate. The group of amidines was also tested for their ability to kill intracellular M.tb. residing in mouse J774A.1 macrophages. Finally, we report on a correlation between the structural differences of the compounds and their anti-mycobacterial activity.