5435-45-0 Usage
Description
(2E)-2-phenylmethoxyiminobutanoic acid, also known as benzyl butenyl amide, is a chemical compound with the molecular formula C12H15NO3. It is an imine derivative of butanoic acid, with a phenyl group attached to the nitrogen atom. (2E)-2-phenylmethoxyiminobutanoic acid possesses potential therapeutic properties, particularly in the field of neuroprotection and neurodegenerative diseases.
Uses
Used in Pharmaceutical Industry:
(2E)-2-phenylmethoxyiminobutanoic acid is used as a neuroprotective agent for its potential role in modulating the activity of peroxisome proliferator-activated receptor gamma (PPARγ), which is involved in various cellular processes. This modulation may contribute to the compound's therapeutic effects in treating neurodegenerative diseases.
Additionally, (2E)-2-phenylmethoxyiminobutanoic acid is being investigated for its potential anti-inflammatory and antioxidant properties, which could further enhance its utility in the development of new pharmaceuticals for treating various conditions. Ongoing research is exploring the biological activity and potential applications of this compound to unlock its full therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 5435-45-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,3 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5435-45:
(6*5)+(5*4)+(4*3)+(3*5)+(2*4)+(1*5)=90
90 % 10 = 0
So 5435-45-0 is a valid CAS Registry Number.
InChI:InChI=1/C11H13NO3/c1-2-10(11(13)14)12-15-8-9-6-4-3-5-7-9/h3-7H,2,8H2,1H3,(H,13,14)/b12-10-
5435-45-0Relevant articles and documents
Chemoenzymatic Production of Enantiocomplementary 2-Substituted 3-Hydroxycarboxylic Acids from l-α-Amino Acids
Pickl, Mathias,Marín-Valls, Roser,Joglar, Jesús,Bujons, Jordi,Clapés, Pere
, p. 2866 - 2876 (2021/04/14)
A two-enzyme cascade reaction plus in situ oxidative decarboxylation for the transformation of readily available canonical and non-canonical l-α-amino acids into 2-substituted 3-hydroxycarboxylic acid derivatives is described. The biocatalytic cascade consisted of an oxidative deamination of l-α-amino acids by an l-α-amino acid deaminase from Cosenzaea myxofaciens, rendering 2-oxoacid intermediates, with an ensuing aldol addition reaction to formaldehyde, catalyzed by metal-dependent (R)- or (S)-selective carboligases namely 2-oxo-3-deoxy-l-rhamnonate aldolase (YfaU) and ketopantoate hydroxymethyltransferase (KPHMT), respectively, furnishing 3-substituted 4-hydroxy-2-oxoacids. The overall substrate conversion was optimized by balancing biocatalyst loading and amino acid and formaldehyde concentrations, yielding 36–98% aldol adduct formation and 91–98% ee for each enantiomer. Subsequent in situ follow-up chemistry via hydrogen peroxide-driven oxidative decarboxylation afforded the corresponding 2-substituted 3-hydroxycarboxylic acid derivatives. (Figure presented.).
