5439-08-7

Basic information

• Product Name: Methyl 3,5-dichloropicolinate
• Synonyms: Methyl 3,5-dichloropicolinate
• CAS NO: 5439-08-7
• Molecular Formula: C₇H₅Cl₂NO₂
• Molecular Weight: 206.0261
• Mol File: 5439-08-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 271.8°Cat760mmHg
• Flash Point: 118.2°C
• Appearance: /
• Density: 1.426g/cm³
• Vapor Pressure: 0.00631mmHg at 25°C
• Refractive Index: 1.548
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: Methyl 3,5-dichloropicolinate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 3,5-dichloropicolinate(5439-08-7)
• EPA Substance Registry System: Methyl 3,5-dichloropicolinate(5439-08-7)

Safety Data

• Hazardous Substances Data: 5439-08-7(Hazardous Substances Data)

Usage

General Description

Methyl 3,5-dichloropicolinate is a chemical compound that belongs to the picolinic acid family and is commonly used in the production of agrochemicals and pharmaceuticals. It is a white, crystalline solid with a molecular formula of C7H5Cl2NO2 and a molecular weight of 202.02 g/mol. Methyl 3,5-dichloropicolinate is known for its herbicidal properties and is often used in the formulation of herbicides to control weeds in various crops. It is important to handle this chemical with care as it can be hazardous to human health and the environment if not properly managed.

InChI:InChI=1/C7H5Cl2NO2/c1-12-7(11)6-5(9)2-4(8)3-10-6/h2-3H,1H3

Upstream product

• 67-56-1 methanol 
• 70151-22-3 methyl 3,5-dichloropicolinic acid chloride 
• 81719-53-1 3,5-dichloropyridine-2-carboxylic acid 
• 846045-08-7 3,5-dichloro-4-hydroxy-pyridine-2-carboxylic acid 
• 5439-04-3 3,4,5-trichloropicolinic acid 
• 200711-45-1 3,4,5-trichloro-pyridine-2-carboxylic acid methyl ester 
• 18107-18-1 diazomethyl-trimethyl-silane 

Downstream Products

• 5468-71-3 3,5-dichloropicolinamide 
• 1202250-84-7 3-chloro-5-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester 
• 1202250-85-8 3,5-bis-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester 
• 1202250-86-9 5-chloro-3-(3-trifluoromethyl-phenyl)-pyridine-2-carboxylic acid methyl ester 
• 1344675-56-4 C₁₈H₂₅ClN₄O₃ 
• 1344675-05-3 C₂₄H₃₁N₅O₄ 

Relevant articles and documents

Preparation method of vadadustat

The invention provides a preparation method of vadadustat, and belongs to the field of pharmaceutical chemical industry. The method comprises the following steps: mixing 3,5-dichloro-2-picolinic acid,methanol and sulfuric acid at a certain temperature, and carrying out a reaction to obtain 3,5-dichloro-2-picolinic acid methyl ester; adding 3-chlorophenylboronic acid, and carrying out a catalyticreaction to obtain 5-(3-chlorphenyl)-3-chloropyridine-methyl formate; and adding glycine into the 5-(3-chlorphenyl)-3-chloropyridine-methyl formate, and carrying out a reaction to obtain the 5-(3-chlorphenyl)-3-chloropyridine-methyl formate. The method has the characteristics of high product purity, high yield, low cost, simple operation and stable process.

FAAH INHIBITORS

The present disclosure relates to compounds useful as inhibitors of the enzyme Fatty Acid Amide Hydrolase (FAAH). The disclosure also provides pharmaceutically acceptable compositions comprising the compounds of the disclosure and methods of using the com