54402-61-8

Basic information

• Product Name: 2-(PYRIDIN-2-YLMETHOXY)BENZALDEHYDE
• Synonyms: 2-(2-Pyridinylmethoxy)benzaldehyde;Benzaldehyde, 2-(2-pyridinylmethoxy)-
• CAS NO: 54402-61-8
• Molecular Formula: C₁₃H₁₁NO₂
• Molecular Weight: 213.24
• Mol File: 54402-61-8.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 370.1±22.0 °C(Predicted)
• Appearance: /
• Density: 1.191±0.06 g/cm3(Predicted)
• PKA: 3.95±0.12(Predicted)
• CAS DataBase Reference: 2-(PYRIDIN-2-YLMETHOXY)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(PYRIDIN-2-YLMETHOXY)BENZALDEHYDE(54402-61-8)
• EPA Substance Registry System: 2-(PYRIDIN-2-YLMETHOXY)BENZALDEHYDE(54402-61-8)

Safety Data

• Hazardous Substances Data: 54402-61-8(Hazardous Substances Data)

Usage

General Description

2-(Pyridin-2-ylmethoxy)benzaldehyde is an organic compound with a chemical formula C13H11NO2. It is a white to yellow solid that is commonly used in the production of pharmaceuticals and organic synthesis. 2-(PYRIDIN-2-YLMETHOXY)BENZALDEHYDE is known for its aromatic and aldehyde functional groups, making it useful for the preparation of various chemical compounds. It is also used as a building block in the synthesis of various heterocyclic compounds. 2-(Pyridin-2-ylmethoxy)benzaldehyde has a wide range of applications in the field of chemistry and pharmaceuticals, making it an important and versatile chemical compound.

Upstream product

• 6959-47-3 2-chloromethylpyridine hydrochloride 
• 90-02-8 salicylaldehyde 
• 4377-33-7 2-chloromethylpyridine 

Downstream Products

• 835627-99-1 2-(pyridin-2-ylmethoxy)-benzaldehyde oxime 
• 835628-08-5 C₃₀H₂₂N₂O₂ 
• 1502812-55-6 C₃₉H₃₇N₅O₃ 
• 7035-05-4 2-(benzofuran-2-yl)pyridine 
• 1549807-70-6 (4-methoxyphenyl)(2-(pyridin-2-ylmethoxy)phenyl)methanone 
• 1016858-44-8 1-[2-(pyridin-2-ylmethoxy)phenyl]ethan-1-one 
• 1549807-80-8 2-(3-(4-methoxyphenyl)benzofuran-2-yl)pyridine 
• 1156101-36-8 1-[2-(pyridin-2-ylmethoxy)phenyl]ethan-1-ol 
• 1549808-94-7 (4-methoxyphenyl)(2-(pyridin-2-ylmethoxy)phenyl)methanol 

Relevant articles and documents

A rhodamine-based turn-on nitric oxide sensor in aqueous medium with endogenous cell imaging: An unusual formation of nitrosohydroxylamine

A new sensor (L3) based on Rhodamine-B-en (2) and 2-(pyridin-2-ylmethoxy)benzaldehyde (1) has been developed for highly sensitive and selective recognition of NO in purely aqueous medium where the reaction of NO with the fluorophore leads to an unusual formation of nitrosohydroxylamine with the selective opening of the spirolactam ring over different cations, anions, amino-acids and other biological species with prominent enhancement in absorption and emission intensities. A large enhancement of fluorescence intensity for NO (11 fold) was observed upon addition of 3 equivalents of NO into the sensor in aqueous HEPES buffer (20 mM) at pH 7.20, μ = 0.05 M NaCl with naked eye detection. The corresponding Kf value was evaluated to be (7.55 ± 2.04) × 104 M-1 from the fluorescence titration plot. Quantum yields of L3 and the [L3 + NO] compound are found to be 0.07 and 0.77, respectively, using Rhodamine-6G as the standard. The LOD for NO was determined by the 3σ method and found to be 83.4 nM. The L3 sensor has low cytotoxicity, and is cell permeable and suitable for in vitro NO sensing. The in vivo compatibility of the sensor was also checked on zebrafish.

TRPML MODULATORS

The present invention provides compounds, pharmaceutically acceptable compositions thereof, and methods of using the same.

Rapid detection of aspartic acid and glutamic acid in water by BODIPY-Based fluorescent probe: Live-cell imaging and DFT studies

Strategically modified4-(diethylamino)-2-(pyridin-2-ylmethoxy)benzaldehyde appended BODIPY-based probe N,N-SP-BPY detects aspartic acid (Asp)and glutamic acid (Glu)by inhibition of Photoinduced electron transfer (PET)process in water. The probe shows cons