5441-28-1

Basic information

• Product Name: 1,4-bis(4-methoxyphenyl)phthalazine
• Synonyms: 1,4-bis(4-methoxyphenyl)phthalazine
• CAS NO: 5441-28-1
• Molecular Formula: C₂₂H₁₈N₂O₂
• Molecular Weight: 342.3905
• Mol File: 5441-28-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 205-206 °C
• Boiling Point: 551 °C at 760 mmHg
• Flash Point: 193.2 °C
• Appearance: /
• Density: 1.186 g/cm³
• Vapor Pressure: 1.26E-11mmHg at 25°C
• Refractive Index: 1.631
• PKA: 3.53±0.30(Predicted)
• CAS DataBase Reference: 1,4-bis(4-methoxyphenyl)phthalazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-bis(4-methoxyphenyl)phthalazine(5441-28-1)
• EPA Substance Registry System: 1,4-bis(4-methoxyphenyl)phthalazine(5441-28-1)

Safety Data

• Hazardous Substances Data: 5441-28-1(Hazardous Substances Data)

Usage

Appearance

White to off-white powder

Melting point

224-226°C

Organic electronics

Thin-film transistor material for electronic devices

Antimicrobial properties

Investigated for its ability to inhibit the growth of microorganisms

Antioxidant properties

Studied for its potential to neutralize harmful free radicals

Synthesis

Used as a building block in the synthesis of other organic compounds

Research areas

Pharmaceutical and material science

Structure

Contains a phthalazine core with two 4-methoxyphenyl groups attached to the 1 and 4 positions

InChI:InChI=1/C22H18N2O2/c1-25-17-11-7-15(8-12-17)21-19-5-3-4-6-20(19)22(24-23-21)16-9-13-18(26-2)14-10-16/h3-14H,1-2H3

Upstream product

• 104-92-7 1-bromo-4-methoxy-benzene 
• 696-62-8 para-iodoanisole 
• 112219-63-3 (4-methoxyphenyl)magnesium iodide 
• 7477-32-9 acide (dimethoxy-4'4 diphenylmethyl)-2 benzoique 
• 6306-97-4 1,3-bis(4-methoxyphenyl)isobenzofuran 
• 5449-71-8 methyl 2-(4-methoxybenzoyl)benzoate 
• 85-44-9 phthalic anhydride 
• 7477-28-3 o-bis(p-methoxyphenoyl)benzene 

Relevant articles and documents

1. 4 - (hydroxy-phenyl) II - 2, 3 - naphthyridine derivatives and their synthetic method

The invention discloses 1,4-di(para hydroxybenzene) based-2,3-quinazoline and a synthesis method thereof. In the synthesis method, a Grignard reagent is prepared from para-halogen anisole and magnesium ribbons and is reacted with phthalic anhydride in a tetrahydrofuran/toluene, 2-methyl tetrahydrofuran/toluene, or diethyl ether/toluene mixing solvent to obtain benzol-1,2-di(para-methoxyl)benzophenone; under the solvent of glacial acetic acid or alcohol, the benzol-1,2-bi(para-methoxyl)benzophenone is reacted again with hydrazine hydrate to obtain 2,3-quinazoline1,4-bi-hydroxybenzene; and finally the 2,3-quinazoline1,4-bi-hydroxybenzene is demethylated under the participation of 40 percent of hydrobromic acid by taking the glacial acetic acid as the solvent to obtain the product. The invention provides a new monomer for developing a high-property polymer material with a quinazoline structure. The invention has reasonable and simple selection for a technical route as well as convenience and easy operation and provides a successful synthesis method for the synthesis of the intermediate of the high polymer product technically.