54419-21-5

Basic information

• Product Name: 3',4'-dimethoxybutyrophenone
• Synonyms: 3',4'-dimethoxybutyrophenone;1-(3,4-Dimethoxyphenyl)-1-butanone
• CAS NO: 54419-21-5
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.25364
• EINECS: 259-159-1
• Mol File: 54419-21-5.mol
• Article Data: 16

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3',4'-dimethoxybutyrophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 3',4'-dimethoxybutyrophenone(54419-21-5)
• EPA Substance Registry System: 3',4'-dimethoxybutyrophenone(54419-21-5)

Safety Data

• Hazardous Substances Data: 54419-21-5(Hazardous Substances Data)

Usage

General Description

3',4'-Dimethoxybutyrophenone is a chemical compound with the molecular formula C13H16O3. It is a synthetic derivative of butyrophenone and belongs to the class of psychoactive substances. The compound is known for its sedative and tranquilizing effects and is used in some countries as a sedative and antiemetic medication. It acts as a dopamine antagonist, blocking the effects of dopamine in the brain, and is believed to contribute to its sedative properties. 3',4'-Dimethoxybutyrophenone is also used as a research chemical to study the effects of dopamine antagonists and their potential therapeutic applications. Due to its psychoactive properties, the compound is considered to have abuse potential and is regulated in some jurisdictions.

Upstream product

• 106-31-0 butanoic acid anhydride 
• 91-16-7 1,2-dimethoxybenzene 
• 141-75-3 butyryl chloride 
• 107-92-6 butyric acid 
• 69638-92-2 1,2-butyrideneacetate 
• 16613-23-3 3,4-Dimethoxyphenyl-2-piperidinopropyl-keton 
• 927-77-5 n-propylmagnesium bromide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 497-19-8 sodium carbonate 
• 68719-74-4 1,2-Dimethoxy-4-((E)-pent-1-enyl)-benzene 
• 17386-89-9 4-Butyroylpyrocatechol 
• 74-88-4 methyl iodide 
• 4378-55-6 5-(3,4-dimethoxy-phenyl)-5-oxo-pentanoic acid 

Downstream Products

• 59056-76-7 1,2-dimethoxy-4-butylbenzene 
• 54419-22-6 1-(3,4-dimethoxy-phenyl)-butan-1-ol 
• 172988-62-4 ethyl 5-(3,4-dimethoxyphenyl)-4-ethyl-3,5-dioxopentanoate 
• 76252-28-3 trans-4-(3′,4′-dimethoxyphenyl)but-3-ene 
• 107275-71-8 2-butyl-4,5-dimethoxy-trans-cinnamic acid 
• 101268-19-3 2-butyl-4,5-dimethoxy-benzaldehyde 
• 2525-05-5 1,2-dihydroxy-4-butylbenzene 
• 101589-34-8 2-butyl-4,5-dimethoxy-benzenesulfonic acid amide 
• 1613322-14-7 C₁₄H₂₂O₄ 
• 1604832-27-0 (E)-N-(1-(3,4-dimethoxyphenyl)butylidene)-2,2-diethoxyethanamine 
• 23474-83-1 2-bromo-1-(3,4-dimethoxyphenyl)butan-1-one 

Relevant articles and documents

Direct Hydrodecarboxylation of Aliphatic Carboxylic Acids: Metal- and Light-Free

A mild and inexpensive method for direct hydrodecarboxylation of aliphatic carboxylic acids has been developed. The reaction does not require metals, light, or catalysts, rendering the protocol operationally simple, easy to scale, and more sustainable. Crucially, no additional H atom source is required in most cases, while a broad substrate scope and functional group tolerance are observed.

A template-free approach to nanotube-decorated polymer surfaces using 3,4-phenylenedioxythiophene (PhEDOT) monomers

In this work, novel 3,4-phenylenedioxythiophene (PhEDOT) monomers with alkyl, branched, and aromatic substituents were synthesized and tested for their efficacy at forming surfaces with unique wetting properties and surface morphology without the aid of surfactants. Monomers with a naphthalene substituent clearly showed the highest capacity to stabilize gas bubbles (O2 or H2) formed in solution during electrodeposition from trace water, resulting in the formation of nanotubes. Variation in the resulting density, diameter, and height of nanotubes was demonstrated by varying the electropolymerization protocol, conditions, or electrolyte used. The wetting induced by the nanotube formation results in the surfaces formed having both high contact angles with water (W) and strong adhesion, despite all polymers being intrinsically hydrophilic. This one-step and easily tunable approach to nanotube formation has potential to advance applications in membrane design, water transport and harvesting, as well as sensor design.

SUBSTITUTED 6, 7-DIALKOXY-3-ISOQUINOLINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASE 10 (PDE 10A)

The invention relates to compounds of the formula or a pharmaceutically acceptable salt thereof, wherein R′, R1 through R7 and Ar are as defined herein. These compounds are useful as inhibitors of phosphodiesterase 10 (PDE10A) which are useful in treating central nervous system diseases such as psychosis and also in treating, for example, obesity, type II diabetes, metabolic syndrome, glucose intolerance, pain and ophthalmic diseases.