54433-49-7

Basic information

• Product Name: 1H-Pyrrole-2,5-dione, 1-methyl-3-phenyl-
• CAS NO: 54433-49-7
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.198
• Mol File: 54433-49-7.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1H-Pyrrole-2,5-dione, 1-methyl-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrrole-2,5-dione, 1-methyl-3-phenyl-(54433-49-7)
• EPA Substance Registry System: 1H-Pyrrole-2,5-dione, 1-methyl-3-phenyl-(54433-49-7)

Safety Data

• Hazardous Substances Data: 54433-49-7(Hazardous Substances Data)

Usage

Type of compound

Heterocyclic organic compound (contains a ring structure with atoms of at least two different elements)

Reactivity

Commonly used in organic synthesis and pharmaceutical research

Color

Yellow

Uses

pH indicator in some applications

Potential therapeutic properties

Anti-inflammatory and anti-tumor effects.

Upstream product

• 201230-82-2 carbon monoxide 
• 536-74-3 phenylacetylene 
• 74-89-5 methylamine 
• 86-34-0 phensuximide 
• 36122-35-7 2-phenylmaleic anhydride 
• 1159989-28-2 C₁₁H₁₀ClNO₂ 
• 930-88-1 N-methylmaleimide 
• 98-80-6 phenylboronic acid 

Downstream Products

• 86-34-0 (R)-1-methyl-3-phenylpyrrolidine-2,5-dione 
• 88905-25-3 7,7-Dimethoxy-3-methyl-1-phenyl-3-aza-bicyclo[3.2.0]heptane 
• 88905-21-9 7,7-Dimethoxy-3-methyl-1-phenyl-3-aza-bicyclo[3.2.0]heptane-2,4-dione 
• 86-34-0 phensuximide 

Relevant articles and documents

Palladium-catalyzed aerobic oxidative carbonylation of alkynes with amines: a general access to substituted maleimides

A catalytic oxidative carbonylation reaction was developed for the synthesis of polysubstituted maleimides from alkynes and amines with air as a green oxidant. This novel transformation proceeds in the presence of palladium chloride without the need for expensive ligands or additives and has a broad substrate scope affording a variety of maleimides in good to high yields.

Inhibition of monoamine oxidase B by N-methyl-2-phenylmaleimides

Based on a recent report that 1-methyl-3-phenylpyrrolyl analogues are moderately potent reversible inhibitors of the enzyme monoamine oxidase B (MAO-B), a series of structurally related N-methyl-2-phenylmaleimidyl analogues has been prepared and evaluated