544462-63-7

Basic information

• Product Name: 1-(ethylsulfonyl)-4-{4-nitrophenyl}piperazine
• Synonyms: 1-(ethylsulfonyl)-4-{4-nitrophenyl}piperazine
• CAS NO: 544462-63-7
• Molecular Formula: C₁₂H₁₇N₃O₄S
• Molecular Weight: 299.34608
• Mol File: 544462-63-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(ethylsulfonyl)-4-{4-nitrophenyl}piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(ethylsulfonyl)-4-{4-nitrophenyl}piperazine(544462-63-7)
• EPA Substance Registry System: 1-(ethylsulfonyl)-4-{4-nitrophenyl}piperazine(544462-63-7)

Safety Data

• Hazardous Substances Data: 544462-63-7(Hazardous Substances Data)

Usage

Description

1-(ethylsulfonyl)-4-4-nitrophenylpiperazine, a chemical compound with the molecular formula C13H20N4O4S, is a derivative of piperazine featuring a sulfonylethyl group attached to the nitrogen atom and a 4-nitrophenyl group connected to the piperazine ring. 1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is recognized for its potential interactions with various biological targets, positioning it as a promising candidate in the fields of medicinal chemistry and pharmaceutical research.

Uses

Used in Pharmaceutical Research:
1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is utilized as a potential drug candidate in pharmaceutical research for its ability to engage with multiple biological targets, offering a wide range of therapeutic applications.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is used as an active agent to combat various types of infections, leveraging its interactions with biological targets to inhibit microbial growth.
Used in Antiparasitic Applications:
1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is employed as an antiparasitic agent, particularly effective against a variety of parasites, due to its capacity to interfere with their biological processes.
Used in Anticancer Applications:
Within oncology, 1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is used as a potential anticancer agent, exhibiting properties that may help in the treatment of various types of cancer by targeting and disrupting cancer cell processes.
Used in Neurological Disorder Treatment:
1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is used as a therapeutic agent for neurological disorders, with preclinical studies demonstrating its potential to alleviate symptoms and improve patient outcomes.
Used in Psychiatric Condition Management:
In the treatment of psychiatric conditions, 1-(ethylsulfonyl)-4-4-nitrophenylpiperazine is used as a potential agent to help manage symptoms and improve the quality of life for individuals suffering from such conditions.

Upstream product

• 6269-89-2 1-(4-Nitrophenyl)piperazine 
• 594-44-5 Ethanesulfonyl chloride 
• 62937-96-6 1-ethanesulfonylpiperazine 
• 350-46-9 4-Fluoronitrobenzene 
• 105297-10-7 4-(4-aminophenyl)thiomorpholine 1,1-dioxide 
• 329943-64-8 4-(4-nitrophenyl)thiomorpholine 1,1-dioxide 
• 1009576-98-0 tert-butyl 4-(ethylsulfonyl)piperazine-1-carboxylate 

Downstream Products

• 611400-14-7 4-[4-(ethylsulfonyl)-1-piperazin-1-yl]phenylamine 
• 1620488-73-4 1-(4-fluorophenyl)-2-imidazol-1-yl-ethyl N-[4-(4-ethylsulfonylpiperazin-1-yl)phenyl]carbamate 

Relevant articles and documents

COMPOUNDS AND THEIR USES AS SPLEEN TYROSINE KINASE INHIBITORS

Provided are compounds of Formula (I) which can be used as Syk inhibitors and potently as therapeutic agents against diseases mediated by Syk.

CHROMAN COMPOUNDS AS 5-HT1B ANTAGONISTS

Chroman derivatives according to formula (I), wherein R1, R2, R3 and R4 are as defined in the specification, pharmaceutically-acceptable salts, methods of making, pharmaceutical compositions containing and methods for using the same. The compounds are 5-HT1B antagonists and are useful in the treatment of mood and anxiety disorders .as well as cognitive disorders.