544476-92-8

Basic information

• Product Name: (S)-3-Benzyl-4-[(R)-1-hydroxy-12-(tetrahydro-pyran-2-yloxy)-dodec-2-ynyl]-oxazolidin-2-one
• Synonyms: (S)-3-Benzyl-4-[(R)-1-hydroxy-12-(tetrahydro-pyran-2-yloxy)-dodec-2-ynyl]-oxazolidin-2-one
• CAS NO: 544476-92-8
• Molecular Weight: 457.61
• Mol File: 544476-92-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-3-Benzyl-4-[(R)-1-hydroxy-12-(tetrahydro-pyran-2-yloxy)-dodec-2-ynyl]-oxazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-3-Benzyl-4-[(R)-1-hydroxy-12-(tetrahydro-pyran-2-yloxy)-dodec-2-ynyl]-oxazolidin-2-one(544476-92-8)
• EPA Substance Registry System: (S)-3-Benzyl-4-[(R)-1-hydroxy-12-(tetrahydro-pyran-2-yloxy)-dodec-2-ynyl]-oxazolidin-2-one(544476-92-8)

Safety Data

• Hazardous Substances Data: 544476-92-8(Hazardous Substances Data)

Upstream product

• 544476-90-6 2-(11,11-dibromo-undec-10-enyloxy)-tetrahydro-pyran 
• 51953-88-9 1-[(tetrahydropyran-2-yl)oxy]undec-10-yne 
• 81965-50-6 10-(tetrahydropyran-2'-yloxy)decanal 
• 112-47-0 1,10-Decanediol 
• 43047-93-4 10-tetrahydropyranyloxydecanol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 544476-91-7 (S)-3-Benzyl-4-[12-(tetrahydro-pyran-2-yloxy)-dodec-2-ynoyl]-oxazolidin-2-one 

Relevant articles and documents

Synthesis of fluorescence-labeled sphingosine and sphingosine 1-phosphate; Effective tools for sphingosine and sphingosine 1-phosphate behavior

A fluorescence-labeled sphingosine and sphingosine 1-phosphate have been successfully synthesized from the oxazolidinone methyl ester derived from glycidol via monoalkylation and the stereoselective reduction of the resulting ketone. The labeled sphingosine was converted into its phosphate by treatment with sphingosine kinase 1 (SPHK1) from mouse, and in platelets, and it was incorporated into the Chinese Hamster Ovarian (CHO) cells. In addition, MAPK was activated by NBD-Sph-1-P through Edg-1, Sph-1-P receptor.