54449-47-7

Basic information

• Product Name: Benzamide, N-(2,2-dimethylpropyl)-
• CAS NO: 54449-47-7
• Molecular Formula: C12H17NO
• Molecular Weight: 191.273
• Mol File: 54449-47-7.mol
• Article Data: 10

Chemical Properties

• CAS DataBase Reference: Benzamide, N-(2,2-dimethylpropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, N-(2,2-dimethylpropyl)-(54449-47-7)
• EPA Substance Registry System: Benzamide, N-(2,2-dimethylpropyl)-(54449-47-7)

Safety Data

• Hazardous Substances Data: 54449-47-7(Hazardous Substances Data)

Upstream product

• 5813-64-9 2.2-dimethylpropylamine 
• 98-88-4 benzoyl chloride 
• 959-22-8 p-nitrophenylbenzoate 
• 65-85-0 benzoic acid 
• 630-19-3 pivalaldehyde 
• 55-21-0 benzamide 
• 614-45-9 tert-Butyl peroxybenzoate 
• 85909-02-0 N-benzyl-N-(tert-butoxycarbonyl)-benzamide 

Downstream Products

• 89549-37-1 N-pivaloyl benzamide 

Relevant articles and documents

Method for synthesizing amide compounds by using N-Boc amide as substrate

The invention relates to a method for synthesizing amide compounds by using N-Boc amide as a substrate. According to the method, N-Boc amide and various amine compounds are subjected to an intermolecular nucleophilic substitution reaction in an organic solvent so as to efficiently prepare various amide compounds. The method has the advantages of mild reaction conditions, simple and convenient operation, high yield and good functional group compatibility.

Catalyst and method for producing the same

PROBLEM TO BE SOLVED: To provide a method for producing an amide compound from a primary alcohol and at least one selected from a primary amine, a secondary amine and derivatives of those under relatively mild conditions with high selectivity and a high conversion ratio.SOLUTION: A method for producing an amide compound comprises a step of obtaining the amide compound from a primary alcohol and at least one selected from a primary amine, a secondary amine and derivatives of those, in the presence of a catalyst comprising a carrier formed by crosslinking a crosslinkable functional group of a styrene-based polymer having a side chain containing the crosslinkable functional group, and a nanosize cluster and carbon black supported on the carrier, wherein the nanosize cluster is at least one selected from a nanosize gold cluster and a nanosize cluster of gold and at least one group 8 metal selected from iron, cobalt and nickel.

Selective formation of secondary amides via the copper-catalyzed cross-coupling of alkylboronic acids with primary amides

For the first time, a general catalytic procedure for the cross-coupling of primary amides and alkylboronic acids is demonstrated. The key to the success of this reaction was the identification of a mild base (NaOSiMe3) and oxidant (di-tert-butyl peroxide) to promote the copper-catalyzed reaction in high yield. This transformation provides a facile, high-yielding method for the monoalkylation of amides.