5445-44-3 Usage
Description
O-Benzyl-DL-Serine is a white crystalline compound that serves as a versatile building block in the synthesis of various organic compounds. It is an amino acid derivative with a benzyl group attached to the oxygen atom of the serine molecule, which provides unique chemical properties and reactivity.
Uses
Used in Pharmaceutical Industry:
O-Benzyl-DL-Serine is used as a catalytic agent for the synthesis of various pharmaceutical compounds. Its unique structure allows it to participate in a range of chemical reactions, facilitating the production of drugs with specific therapeutic properties.
Used in Petrochemical Industry:
In the petrochemical industry, O-Benzyl-DL-Serine is utilized as an additive to enhance the performance of certain products. Its chemical properties contribute to improving the characteristics of petrochemical products, such as their stability, reactivity, or other desirable attributes.
Check Digit Verification of cas no
The CAS Registry Mumber 5445-44-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 5 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5445-44:
(6*5)+(5*4)+(4*4)+(3*5)+(2*4)+(1*4)=93
93 % 10 = 3
So 5445-44-3 is a valid CAS Registry Number.
InChI:InChI=1/C10H13NO3/c11-9(10(12)13)7-14-6-8-4-2-1-3-5-8/h1-5,9H,6-7,11H2,(H,12,13)
5445-44-3Relevant articles and documents
AMINO ACIDS; 13. INVESTIGATIONS ON THE SYNTHESIS OF DL-SERINE FROM α-HALOACRYLIC ACID DERIVATIVES
Effenberger, Franz,Zoller, Gerhard
, p. 5573 - 5582 (2007/10/02)
The alkoxide-catalyzed addition of alcohols 2 to α-chloroacrylonitrile (1) at -35 degC gives rise to 3-alkoxy-2-chloropropanenitriles 3; at 0-5 degC with excess 2 alkyl 3-alkoxy-2-chloropropanimidates 4 are obtained.The yields of 3 or 4 decrease with increasing pKa values of the alcohols 2.In the basecatalyzed addition of phenols 5 to 1, a temperature-dependent addition equilibrium is set up in which the position of equilibrium is shifted in favour of the addition products 6 with increasing pKa values of 5.The 3-alkoxy-2-chloropropanoates 8, which are readily accessible by hydrolysis of 4, react smoothly with sodium azide in the presence of a phase transfer catalyst to furnish the 3-alkoxy-2-azidopropanoates 10.Starting from benzyl 2-azido-3-benzyloxy-propanoate (10b), the specific syntheses of DL-serine (14), DL-serine hydrochloride (14*HCl), DL-serine methyl ester hydrochloride (13a*HCl), O-benzyl-DL-serine (12b), and O-benzyl-DL-serine benzyl ester hydrochloride (11b*HCl) are possible by variation of the hydrogenation conditions.