5446-17-3

Basic information

• Product Name: (2-chloro-5-Methylphenyl)hydrazine hydrochloride
• Synonyms: (2-chloro-5-Methylphenyl)hydrazine hydrochloride;(2-Chloro-5-methyl-phenyl)-hydrazine;1-(5-Chloro-2-methylphenyl)hydrazine hydrochloride
• CAS NO: 5446-17-3
• Molecular Formula: C₇H₉ClN₂*ClH
• Molecular Weight: 193.0737
• Mol File: 5446-17-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 253.8°Cat760mmHg
• Flash Point: 107.3°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 0.0179mmHg at 25°C
• Refractive Index: 1.634
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: (2-chloro-5-Methylphenyl)hydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: (2-chloro-5-Methylphenyl)hydrazine hydrochloride(5446-17-3)
• EPA Substance Registry System: (2-chloro-5-Methylphenyl)hydrazine hydrochloride(5446-17-3)

Safety Data

• Hazardous Substances Data: 5446-17-3(Hazardous Substances Data)

Usage

General Description

"(2-chloro-5-Methylphenyl)hydrazine hydrochloride" is a chemical compound that is derived from hydrazine. It is a hydrazine derivative that contains a chlorine and a methyl group attached to a phenyl ring. It is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various pharmaceuticals and biologically active compounds. The hydrochloride salt form of this compound provides improved stability and solubility in water, making it easier to handle and store. "(2-chloro-5-Methylphenyl)hydrazine hydrochloride" is also used in the preparation of other organic compounds and in various chemical reactions in the laboratory.

InChI:InChI=1/C7H9ClN2/c1-5-2-3-6(8)4-7(5)10-9/h2-4,10H,9H2,1H3

Upstream product

• 95-79-4 5-chloro-2-methyl-benzenamine 

Downstream Products

• 1224944-69-7 1-(5-chloro-2-methylphenyl)-3-methyl-1H-pyrazol-5-amine 
• 1639789-09-5 4-chloro-2-(1-(2,5-dichlorophenyl)-1H-pyrazol-4-yl)-3,3,7-trimethyl-3H-indole 
• 1639789-08-4 4-chloro-2-(1-(2,4-dimethylphenyl)-1H-pyrazol-4-yl)-3,3,7-trimethyl-3H-indole 
• 1639789-07-3 4-chloro-2-(1-(3-chloro-2-methylphenyl)-1H-pyrazol-4-yl)-3,3,7-trimethyl-3H-indole 
• 1639789-06-2 4-chloro-2-(1-(4-chlorophenyl)-1H-pyrazol-4-yl)-3,3,7-trimethyl-3H-indole 
• 1639789-05-1 4-chloro-3,3,7-trimethyl-2-(1-phenyl-1H-pyrazol-4-yl)-3Hindole 
• 76606-55-8 2-(4-chloro-2-methyl-phenyl)-5-methyl-2H-pyrazol-3-ylamine 

Relevant articles and documents

PYRAZOLOPYRIMIDINE JAK INHIBITOR COMPOUNDS AND METHODS

The invention provides JAK kinase inhibitors of Formula Ia, enantiomers, diasteriomers or pharmaceutically acceptable salts thereof, wherein R1, R2, R7 and Z are defined herein, a pharmaceutical composition that includes a compound of Formula Ia and a pharmaceutically acceptable carrier, adjuvant or vehicle, and methods of treating or lessening the severity of a disease or condition responsive to the inhibition of a JAK kinase activity in a patient.