544694-75-9

Basic information

• Product Name: 1-(3-cyano-phenyl)-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester
• CAS NO: 544694-75-9
• Molecular Weight: 255.276
• Mol File: 544694-75-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-cyano-phenyl)-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-cyano-phenyl)-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester(544694-75-9)
• EPA Substance Registry System: 1-(3-cyano-phenyl)-5-methyl-1H-pyrazole-3-carboxylic acid ethyl ester(544694-75-9)

Safety Data

• Hazardous Substances Data: 544694-75-9(Hazardous Substances Data)

Upstream product

• 82874-96-2 2-methoxyimino-4-oxo-pentaneperoxoic acid ethyl ester 
• 2881-99-4 3-cyano-phenylhydrazine hydrochloride 

Downstream Products

• 544694-62-4 4-(4-{[1-(3-carbamimidoyl-phenyl)-5-methyl-1H-pyrazol-3-ylmethyl]-methanesulfonyl-amino}-phenoxy)-piperidine-1-carboxylic acid tert-butyl ester 
• 327047-03-0 3-(3-chloromethyl-5-methyl-pyrazol-1-yl)-benzonitrile 

Relevant articles and documents

Discovery of 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2′-(methylsulfonyl)-[1,1′-b iphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide (DPC423), a highly potent, selective, and orally bioavailable inhibitor of blood coagulation factor Xa

Factor Xa (fXa) plays a critical role in the coagulation cascade, serving as the point of convergence of the intrinsic and extrinsic pathways. Together with nonenzymatic cofactor Va and Ca2+ on the phospholipid surface of platelets or endotheli