54484-71-8

Basic information

• Product Name: 3,3,6-Trimethyl-1-indanone
• Synonyms: 2,3-Dihydro-3,3,6-trimethyl-1H-inden-1-one;3,3,6-Trimethyl-1-indanone;3,3,6-triMethyl-2,3-dihydro-1H-inden-1-one
• CAS NO: 54484-71-8
• Molecular Formula: C₁₂H₁₄O
• Molecular Weight: 174.24
• Mol File: 54484-71-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 42-43℃
• Boiling Point: 283℃
• Flash Point: 118℃
• Appearance: /
• Density: 1.026
• CAS DataBase Reference: 3,3,6-Trimethyl-1-indanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3,6-Trimethyl-1-indanone(54484-71-8)
• EPA Substance Registry System: 3,3,6-Trimethyl-1-indanone(54484-71-8)

Safety Data

• Hazardous Substances Data: 54484-71-8(Hazardous Substances Data)

Upstream product

• 42288-08-4 3-methyl-3-p-tolyl-butyric acid 
• 51380-85-9 3-methyl-3-p-tolyl-butyryl chloride 
• 860257-58-5 3-methyl-3-p-tolyl-butyric acid p-toluidide 
• 144657-82-9 7aα-carbomethoxy-2,3,3aα,4,7,7a-hexahydro-3,3,6-trimethyl-7β-(trimethylsilyloxy)inden-1-one 
• 144657-82-9 7aα-carbomethoxy-2,3,3aα,4,7,7a-hexahydro-3,3,6-trimethyl-7α-(trimethylsilyloxy)inden-1-one 
• 2231-66-5 2,2-dimethyl-5-(propan-2-ylidene)-1,3-dioxane-4,6-dione 
• 872791-94-1 (1-methyl-1-p-tolyl-ethyl)-malonic acid 
• 356535-58-5 5-(2-p-tolylpropane)-(2,2)-dimethyl-(1,3)-dioxane-4,6-dione 
• 54623-57-3 (E)-trimethyl(2-methylbuta-1,3-dienyloxy)silane 
• 60585-44-6 methyl 4,4-dimethyl-2-oxocyclopentanecarboxylate 
• 86576-36-5 3,3-dimethyl-5-oxo-1-cyclopentene-1-carboxylic acid methyl ester 
• 1195-32-0 1-methyl-4-isopropenylbenzene 
• 87306-59-0 2,2-Dichloro-3-methyl-(4-methylphenyl)cyclobutanone 
• 193003-74-6 3-methyl-3-(4-methylphenyl)cyclobutanone 

Downstream Products

• 14656-06-5 1,1,3,5,-tetramethyl-indene 

Relevant articles and documents

NHC Ligand-Enabled, Palladium-Catalyzed Non-Directed C(sp3)-H Carbonylation to Access Indanone Cores

A palladium-catalyzed C(sp3)-H carbonylation of alkylated aryl triflates or bromides under 1 atm of CO has been developed, in which no directing group or oxidant was required. The essence of this reaction is the combination of appropriate NHC l

Synthesis of β,β-disubstituted indanones via the Pd-catalyzed tandem conjugate addition/cyclization reaction of arylboronic acids with α,β-unsaturated esters

Under Pd catalysis with a newly synthesized electron-deficient heterocycle, 2-(4,5-dihydroimidazol-2-yl)- pyrimidine (as the ligand), the reaction of α,β-unsaturated esters with arylboronic acids afforded a wide range of 3,3-disubstituted indan-1-ones bearing a quaternary carbon in high yields. Mechanistic studies revealed that the reaction involves a tandem conjugate addition/1,4-Pd shift followed by a cyclization.

A rhodium(I)-catalysed formal intramolecular C-C/C-H bond metathesis

Phenylcyclobutanes underwent skeletal reorganisation in the presence of Wilkinson's catalyst to afford indanes through a cascade process involving chelation-assisted C-C bond cleavage and intramolecular C-H bond cleavage.