5449-49-0

Basic information

• Product Name: biphenyl-2-yl benzoate
• CAS NO: 5449-49-0
• Molecular Formula: C₁₉H₁₄O₂
• Molecular Weight: 274.3133
• Mol File: 5449-49-0.mol
• Article Data: 10

Chemical Properties

• Boiling Point: 471.9°C at 760 mmHg
• Flash Point: 199.8°C
• Density: 1.151g/cm³
• Vapor Pressure: 4.48E-09mmHg at 25°C
• Refractive Index: 1.609
• CAS DataBase Reference: biphenyl-2-yl benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: biphenyl-2-yl benzoate(5449-49-0)
• EPA Substance Registry System: biphenyl-2-yl benzoate(5449-49-0)

Safety Data

• Hazardous Substances Data: 5449-49-0(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 90-43-7 2-Phenylphenol 
• 65-85-0 benzoic acid 
• 129103-70-4 2-iodophenyl benzoate 
• 71-43-2 benzene 
• 108-90-7 chlorobenzene 
• 98-88-4 benzoyl chloride 
• 4688-76-0 2-Biphenylboronic acid 
• 591-50-4 iodobenzene 
• 50978-45-5 3-oxobenzo[d]isothiazole-2(3H)-carbaldehyde 1,1-dioxide 
• 2446-51-7 N-methoxybenzamide 
• 201230-82-2 carbon monoxide 
• 58585-84-5 1,3-dioxoisoindolin-2-yl benzoate 
• 2113-51-1 2-iodobiphenyl 

Relevant articles and documents

Visible light-mediated transition metal-free esterification of amides with boronic acids

A novel strategy for visible light-mediated esterification of amides with boronic acids in air has been described. This method is characterized by mild reaction conditions and low cost owing to no need of any catalyst, which implies high potential utility in late-stage functionalization of amide drugs and materials.

Method for preparing carboxylate aryl type compound

The invention belongs to the field of drug synthesis and in particular relates to a method for preparing a carboxylate aryltype compound. The preparation method provided by the invention comprises thefollowing steps: providing a compound A of a formula a shown in the description, a compound B of a formula b shown in the description, an organic palladium complex, and a silver salt, wherein the organic palladium complex is composed of a palladium compound and a nitrogen-containing ligand; the nitrogen-containing ligand comprises an o-phenoline compound and/or a bipyridine compound; and mixing the compound A, the compound B, the organic palladium complex and the silver salt in a reaction solvent, and performing a reaction in an inert gas atmosphere, so as to obtain the carboxylate aryl typecompound of a formula I shown in the description. As the organic palladium complex and the silver salt are simultaneously used, direct selectivity C-O coupling of carboxylic acid and halogenated aromatic hydrocarbon is realized, and the method is applicable to a variety of carboxylic acid substrates and halogenated aromatic substrates, and is wide in compatibility and high in yield.

Nickel-Catalyzed Cross-Coupling of Aryl Redoxactive Esters with Aryl Zinc Reagents

A nickel-catalyzed aryl-aroyloxyl C(sp2)-O radical cross-coupling reaction conducted using a redox active ester with aryl zinc reagent was developed. This method demonstrates a new disconnection approach for formation of aryl aryl esters. In the one-pot sequential process, the readily available aryl carboxylic acids can be converted into functionalized aryl aryl esters and heteroaryl esters. This protocol is amenable to the gram-scale synthesis. The present method has a wide substrate scope and high functional group tolerance.