5449-87-6 Usage
General Description
1,2,5-TRIMETHYL-1H-PYRROLE-3-CARBALDEHYDE is a chemical compound with the molecular formula C9H11NO. It is a derivative of pyrrole and is classified as an aldehyde. The compound is commonly used in the field of organic chemistry as a building block for the synthesis of more complex molecules. It is also known for its distinct odor and is used in the production of flavor and fragrance compounds. Additionally, 1,2,5-TRIMETHYL-1H-PYRROLE-3-CARBALDEHYDE has been the subject of research in the field of pharmaceuticals due to its potential biological activity and medicinal properties. However, further studies are needed to fully understand its therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 5449-87-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,4 and 9 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5449-87:
(6*5)+(5*4)+(4*4)+(3*9)+(2*8)+(1*7)=116
116 % 10 = 6
So 5449-87-6 is a valid CAS Registry Number.
InChI:InChI=1/C8H11NO/c1-6-4-8(5-10)7(2)9(6)3/h4-5H,1-3H3
5449-87-6Relevant articles and documents
Discovery and optimisation studies of antimalarial phenotypic hits
Mital, Alka,Murugesan, Dinakaran,Kaiser, Marcel,Yeates, Clive,Gilbert, Ian H.
supporting information, p. 530 - 538 (2015/10/12)
There is an urgent need for the development of new antimalarial compounds. As a result of a phenotypic screen, several compounds with potent activity against the parasite Plasmodium falciparum were identified. Characterization of these compounds is discussed, along with approaches to optimise the physicochemical properties. The in vitro antimalarial activity of these compounds against P. falciparum K1 had EC50 values in the range of 0.09e29 mM, and generally good selectivity (typically >100-fold) compared to a mammalian cell line (L6). One example showed no significant activity against a rodent model of malaria, and more work is needed to optimise these compounds.
