545-16-4 Usage
Description
(3α)-Tazettine is a naturally occurring alkaloid derived from various plant species, including Daffodils and Narcissus. It belongs to the Amaryllidaceae alkaloids group and is recognized for its potential biological activities, particularly in the areas of anti-cancer properties and as an acetylcholinesterase inhibitor.
Uses
Used in Pharmaceutical Industry:
(3α)-Tazettine is used as an anti-cancer agent for its potential to inhibit the growth of cancer cells. Research suggests that this compound could be a promising candidate in the development of treatments for various types of cancer.
Used in Neurodegenerative Disease Treatment:
(3α)-Tazettine is used as an acetylcholinesterase inhibitor, making it a potential candidate for the treatment of neurodegenerative diseases such as Alzheimer's. Its ability to inhibit acetylcholinesterase may help improve cognitive function and slow the progression of these diseases.
Further research is ongoing to explore the pharmacological and therapeutic potential of (3α)-Tazettine, with the aim of expanding its applications and understanding its full range of effects on human health.
Check Digit Verification of cas no
The CAS Registry Mumber 545-16-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,4 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 545-16:
(5*5)+(4*4)+(3*5)+(2*1)+(1*6)=64
64 % 10 = 4
So 545-16-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H21NO5/c1-19-9-18(20)17(4-3-12(21-2)6-16(17)19)13-7-15-14(22-10-23-15)5-11(13)8-24-18/h3-5,7,12,16,20H,6,8-10H2,1-2H3/t12-,16-,17-,18+/m0/s1
545-16-4Relevant articles and documents
Total syntheses of (-)-haemanthidine, (+)-pretazettine, and (+)-tazettine
Baldwin, Steven W.,Debenham, John S.
, p. 99 - 102 (2007/10/03)
(matrix presented) Haemanthidine Pretazettine Tazettine The total syntheses of the amaryllidaceae alkaloids haemanthidine, pretazettine, and tazettine as optically pure enantiomers are reported. Using D-mannose as the starting material, the critical relat
ALKALOIDS FROM NARCISSUS CONFUSUS
Bastida, Jaume,Viladomat, Francesc,Llabres, Jose M.,Codina, Carles,Feliz, Miguel,Rubiralta, Mario
, p. 1519 - 1524 (2007/10/02)
Key Word Index - Narcissus confusus; Amaryllidaceae; haemanthamine; galanthamine; N-formylgalanthamine; pretazettine; two-dimensional NMR spectra.We report the isolation of haemanthamine, galanthamine, pretazettine and the new alkaloid N-formylgalanthamine from Narcissus confusus plants.Structural determination was carried out by spectroscopic analyses and application of two-dimensional NMR spectroscopy.
Transformation of tazettine to pretazettine
Kobayashi,Kihara,Shingu,Shingu
, p. 2924 - 2932 (2007/10/04)
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