5452-60-8 Usage
Description
(3R,4S)-3,4-diphenylcyclopentanone is a cyclopentanone chemical compound with a specific '3R' and '4S' stereochemistry. It features a five-membered ring structure with two phenyl (C6H5) groups attached, making it a valuable building block in organic synthesis and medicinal chemistry for the preparation of bioactive compounds and pharmaceuticals.
Uses
Used in Organic Synthesis:
(3R,4S)-3,4-diphenylcyclopentanone is used as a building block for the synthesis of various organic compounds due to its unique structure and reactivity.
Used in Medicinal Chemistry:
(3R,4S)-3,4-diphenylcyclopentanone is used as a key intermediate in the development of pharmaceuticals, contributing to the creation of bioactive molecules with potential therapeutic applications.
Used in Materials Science:
(3R,4S)-3,4-diphenylcyclopentanone has potential applications in the field of materials science, where its unique properties can be utilized to develop new materials with specific characteristics.
Used as a Chiral Auxiliary in Asymmetric Synthesis Reactions:
(3R,4S)-3,4-diphenylcyclopentanone is used as a chiral auxiliary to facilitate asymmetric synthesis reactions, enabling the selective formation of enantiomerically pure compounds, which is crucial in the production of pharmaceuticals and other chiral molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 5452-60-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,4,5 and 2 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5452-60:
(6*5)+(5*4)+(4*5)+(3*2)+(2*6)+(1*0)=88
88 % 10 = 8
So 5452-60-8 is a valid CAS Registry Number.
5452-60-8Relevant articles and documents
Unexpected metal-free transformation of gem-dibromomethylenes to ketones under acetylation conditions
Kimura, Rino,Sawayama, Yusuke,Nakazaki, Atsuo,Miyamoto, Kazunori,Uchiyama, Masanobu,Nishikawa, Toshio
, p. 1035 - 1041 (2015/03/31)
Novel conditions for the transformation of gem-dibromomethylenes to ketones are described. gem-Dibromo compounds were treated with acetic anhydride and triethylamine in dichloromethane/water at room temperature under an air atmosphere to give the corresponding ketones in moderate yields. A radical mechanism is proposed based on experimental results.
Samarium(II) iodide-induced tandem reductive coupling-Dieckmann condensation reaction: One-step synthesis of bicyclic oxacyclopentanecarboxylate from bis-α,β-unsaturated esters
Shinohara, Ikuo,Okue, Masayuki,Yamada, Yasuji,Nagaoka, Hiroto
, p. 4649 - 4652 (2007/10/03)
The tandem cyclization of bis-α,β-unsaturated esters with SmI2-Sm-THF in the presence of catalytic amount of methanol was found to stereoselectively provide bicyclo[4.3.0]nonan-8-ones and bicyclo[3.3.0]octan-3-ones.
