5453-03-2

Basic information

• Product Name: 3-benzoyl-2-phenyl-4H-chromen-4-one
• CAS NO: 5453-03-2
• Molecular Formula: C₂₂H₁₄O₃
• Molecular Weight: 326.3448
• Mol File: 5453-03-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 482.9°C at 760 mmHg
• Flash Point: 213.1°C
• Density: 1.283g/cm³
• Vapor Pressure: 1.75E-09mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: 3-benzoyl-2-phenyl-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-benzoyl-2-phenyl-4H-chromen-4-one(5453-03-2)
• EPA Substance Registry System: 3-benzoyl-2-phenyl-4H-chromen-4-one(5453-03-2)

Safety Data

• Hazardous Substances Data: 5453-03-2(Hazardous Substances Data)

Upstream product

• 112037-80-6 2'-hydroxy-2-benzoyl-3-phenyl-acrylophenone 
• 118-93-4 o-hydroxyacetophenone 
• 93-97-0 benzoic acid anhydride 
• 4010-33-7 2-acetylphenyl benzoate 
• 24467-44-5 3-benzylidene-2-phenyl-2,3-dihydro-4H-1-benzopyran-4-one 
• 119139-39-8 3-(Hydroxy-phenyl-methyl)-2-phenyl-chromen-4-one 
• 169693-76-9 3-phenyl-5-(2-benzoyloxyphenyl)isoxazole 
• 98-88-4 benzoyl chloride 
• 1469-94-9 1-(2-hydroxyphenyl)-3-phenyl-1,3-propanedione 
• 24467-41-2 (E)-3-benzylideneflavanone 
• 100-52-7 benzaldehyde 
• 533-58-4 2-Iodophenol 
• 129103-70-4 2-iodophenyl benzoate 
• 1415384-88-1 2-(3-phenylprop-2-ynoyl)phenyl benzoate 

Downstream Products

• 35614-55-2 3-benzylamino-1-(2-hydroxyphenyl)-3-phenyl-2-propenone 
• 75618-65-4 [3-(2-hydroxy-phenyl)-5-phenyl-isoxazol-4-yl]-phenyl-methanone 
• 525-82-6 FLAVONE 
• 98153-12-9 3-iodo-2-phenyl-4H-1-benzopyran-4-one 
• 17317-75-8 3-benzylamino-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one 

Relevant articles and documents

Kinetics and mechanism of certain benzoylation reactions under Vilsmeier-Haack conditions using benzamide and oxychloride in acetonitrile medium

Vilsmeier-Haack (VH) benzoylation reactions with benzaldehydes and acetophenones in acetonitrile medium obeyed second-order reaction kinetics. Under kinetic conditions, the reactions afforded benzoyl derivatives irrespective of the nature of oxychloride (

A concise synthesis of 3-aroylflavones via Lewis base 9-azajulolidine- catalyzed tandem acyl transfer-cyclization

Lewis base-catalyzed tandem acyl transfer-cyclization of acylated o-alkynoylphenols leading to 3-aroylflavones was developed. 9-Azajulolidine smoothly promoted the reaction of the aroyl derivatives at ambient temperature, and the structure-diversed synthesis of 3-aroylflavones with distinct substituents was achieved in moderate to excellent yields.

Synthesis and properties of 3-acyl-γ-pyrones, a novel class of flavones and chromones

Using modified Baker-Venkataraman reaction a novel class of 3-acyl flavones and chromones have been synthesised. Reaction mechanism for their formation have been elucidated. The properties of 3-acyl flavonoids indicate them to be precursors for the synthesis of flavones.