54533-84-5Relevant articles and documents
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Helgeson,R.C. et al.
, p. 6762 - 6763 (1974)
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NOVEL AROMATIC COMPOUND AND USE THEREOF
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Paragraph 0537-0539, (2016/08/17)
Provided is a compound showing a bone formation promoting action (and/or bone resorption suppressive action). A compound of the formula (I) or a pharmacologically acceptable salt: [wherein each substituent is as defined in the DESCRIPTION], has low toxicity, shows good pharmacokinetics, has an action to promote bone formation, and is useful for the prophylaxis or To treatment of metabolic bone diseases (osteoporosis, fibrous osteitis (hyperparathyroidism), osteomalacia, Paget's disease that influences the systemic bone metabolism parameter etc.) associated with a decrease in the bone formation ability as compared to the bone resorption capacity.
SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF
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Page/Page column 367, (2014/09/29)
Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.