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545376-10-1

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545376-10-1 Usage

Chemical Class

Isoindole-1,3-diones

Molecular Weight

233.26 g/mol

Functional Groups

Hydroxy group (OH)
Methylpropyl group (CH3-CH(CH3)-CH2-)

Derivative

Derived from isoindole

Biological and Pharmacological Activities

Isoindole-1,3-diones are known for their potential biological and pharmacological activities.

Research Potential

Further research may be necessary to explore specific properties and potential uses.

Check Digit Verification of cas no

The CAS Registry Mumber 545376-10-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,4,5,3,7 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 545376-10:
(8*5)+(7*4)+(6*5)+(5*3)+(4*7)+(3*6)+(2*1)+(1*0)=161
161 % 10 = 1
So 545376-10-1 is a valid CAS Registry Number.

545376-10-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[(2S)-4-hydroxybutan-2-yl]isoindole-1,3-dione

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:545376-10-1 SDS

545376-10-1Downstream Products

545376-10-1Relevant articles and documents

SMALL MOLECULES THAT TARGET THE RNA THAT CAUSES ALS

-

Paragraph 00583-00585, (2022/04/03)

Disclosed herein are compounds that selectively bind an expanded transcribed repeat r(G4C2)exp, prevent sequestration of RNA-binding proteins, and inhibit translation of repeat associated non-ATG (RAN) translation responsible for generation of toxic dipeptide repeats underlying diseases such as amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The compounds and their pharmaceutical compositions are useful in treating a disease or condition characterized by an expanded G4C2 repeat RNA (r(G4C2)exp), such as ALS and FTD.

Synthesis and in vitro sodium channel blocking activity evaluation of novel homochiral mexiletine analogs

Carocci, Alessia,Catalano, Alessia,Bruno, Claudio,Lentini, Giovanni,Franchini, Carlo,De Bellis, Michela,De Luca, Annamaria,Camerino, Diana Conte

scheme or table, p. 299 - 307 (2010/10/21)

New chiral mexiletine analogs were synthesized in their optically active forms and evaluated in vitro as use-dependent blockers of skeletal muscle sodium channels. Tests carried out on sodium currents of single muscle fibers of Rana esculenta demonstrated

2,3,4,5-TETRAHYDRO-1H-1,5-BENZODIAZEPINE DERIVATIVE AND MEDICINAL COMPOSITION

-

, (2008/06/13)

The present invention has its object to provide a 2,3,4,5-tetrahydro-1H-1,5-benzodiazepine derivative represented with the Formula (1) , or the pharmaceutically acceptable salt, which is effective as a therapeutic and prophylactic agent for diabetes, diabetic nephropathy, or glomerulosclerosis.

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