5454-72-8Relevant articles and documents
MACROCYCLIC PEPTIDOMIMETICS FOR ALPHA-HELIX MIMICRY
-
, (2015/11/02)
Methods and compositions are provided for generating macrocyclic peptides constrained by side-chain-to-C-terminus non-peptidic tethers for use as functional and structural mimics of α-helical motifs, including in therapeutic applications. These methods can be used to produce libraries of conformationally constrained peptidomimetics to identify compounds with desired activity properties.