54547-03-4

Basic information

• Product Name: N-(1-adamantyl)-salicylaldamine
• Synonyms: N-(1-adamantyl)-salicylaldamine
• CAS NO: 54547-03-4
• Molecular Weight: 255.36
• Mol File: 54547-03-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: N-(1-adamantyl)-salicylaldamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-(1-adamantyl)-salicylaldamine(54547-03-4)
• EPA Substance Registry System: N-(1-adamantyl)-salicylaldamine(54547-03-4)

Safety Data

• Hazardous Substances Data: 54547-03-4(Hazardous Substances Data)

Upstream product

• 665-66-7 amantadine hydrochloride 
• 90-02-8 salicylaldehyde 
• 768-94-5 1-Adamantanamine 
• 89-95-2 2-methyl-benzyl alcohol 

Relevant articles and documents

Spectroscopic analyses on interaction of Amantadine-Salicylaldehyde, Amantadine-5-Chloro-Salicylaldehyde and Amantadine-o-Vanillin Schiff-Bases with bovine serum albumin (BSA)

In this work, three Tricyclo [3.3.1.1(3,7)] decane-1-amine (Amantadine) Schiff-Bases, Amantadine-Salicylaldehyde (AS), Amantadine-5-Chloro- Salicylaldehyde (AS-5-C) and Amantadine-o-Vanillin (AS-o-V), were synthesized by direct heating reflux method in et

Coumaraz-2-on-4-ylidene: Ambiphilic N-Heterocyclic Carbenes with a Tunable Electronic Structure

Herein, a coumaraz-2-on-4-ylidene (1) as a new example of an ambiphilic N-heterocyclic carbene, having electronic properties that can be fine-tuned, is reported. The N-carbamic and aryl groups on the carbene carbon center provide exceptionally high electrophilicity and nucleophilicity simultaneously to the carbene center, as evidenced by the 77Se NMR chemical shifts of their selenoketone derivatives and the CO stretching strengths of their rhodium carbonyl complexes. Since the precursors of 1 could be synthesized from various functionalized Schiff bases in a practical and scalable manner, the electronic properties of 1 can be fine-tuned in a quantitative and predictable way by using the Hammett σ constant of the functional groups on aryl ring. The facile electronic tuning capability of 1 may be applicable to eliciting novel properties in main-group and transition-metal chemistry.

Synthesis and in vitro virucidal properties of recent 1 substituted adamantan derivatives

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