54605-31-1

Basic information

• Product Name: Cyclohexanol, 2-iodo-1-methyl-, acetate, (1R,2R)-rel-
• CAS NO: 54605-31-1
• Molecular Formula: C9H15IO2
• Molecular Weight: 282.121
• Mol File: 54605-31-1.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Cyclohexanol, 2-iodo-1-methyl-, acetate, (1R,2R)-rel-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanol, 2-iodo-1-methyl-, acetate, (1R,2R)-rel-(54605-31-1)
• EPA Substance Registry System: Cyclohexanol, 2-iodo-1-methyl-, acetate, (1R,2R)-rel-(54605-31-1)

Safety Data

• Hazardous Substances Data: 54605-31-1(Hazardous Substances Data)

Upstream product

• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 291-64-5 cycloheptane 
• 591-49-1 1-methylcyclohex-1-ene 
• 64-19-7 acetic acid 
• 563-68-8 thallium(I) acetate 
• 127-08-2 potassium acetate 
• 1829-26-1 1-acetoxy-1,2-benziodoxol-3-one 

Relevant articles and documents

New iodination reactions of saturated hydrocarbons

Unactivated C-H bonds react with iodine when exposed to trimethylsilyl azide in the presence of a hypervalent iodine reagent or, alternatively, to aqueous H2O2, acetic anhydride, and sodium azide (see scheme). (Chemical Equation Presented).

Activation of alkanes upon reaction with PhI(OAc)2-I2

You can also choose from alkanes! Either mono- or bifunctional iodo derivatives can be prepared from alkanes (see scheme) in an efficient and selective manner by using PhI(OAc)2, I2, and an alcohol.

Reactions of 1-Methyl-4-t-butylcyclohexene and 1-Methylcyclohexene with Thallium(I) Acetate-Iodine

Treatment of 1-methyl-4-t-butylcyclohexene (2) with thallium(I)acetate-iodine in wet acetic acid at 90 deg C gives a complex mixture of products, which differs from that obtained from a Woodward reaction with silver(I) acetate followed by hydrolysis and which includes the unexpected hydroxy-iodoacetate (25).At 20 deg C the thallium(I)-mediated reaction gives a mixture of regioisomeric iodo-acetates.A re-investigation of the reaction of thallium(I) acetate-iodine with 1-methylcyclohexene (1) at 20 deg C has shown that this is not highly regioselective as reported earlier.The actions of KOAc-I2-18-crown-6 and iodine(III) triacetate in acetic acid on the alkenes (1) and (2), and of I2-H2O in tetramethylene sulphone-chloroform on the alkene (2) are reported.