5464-64-2

Basic information

• Product Name: N-Sulfinyl-2-chloroaniline
• Synonyms: N-Sulfinyl-2-chloroaniline;o-Chloro-N-sulfinylaniline;1-chloro-2-(sulfinylamino)benzene
• CAS NO: 5464-64-2
• Molecular Formula: C₆H₄ClNOS
• Molecular Weight: 173.62
• Mol File: 5464-64-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 252.5°C at 760 mmHg
• Flash Point: 106.5°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 0.0307mmHg at 25°C
• Refractive Index: 1.613
• CAS DataBase Reference: N-Sulfinyl-2-chloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: N-Sulfinyl-2-chloroaniline(5464-64-2)
• EPA Substance Registry System: N-Sulfinyl-2-chloroaniline(5464-64-2)

Safety Data

• Hazardous Substances Data: 5464-64-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H4ClNOS/c7-5-3-1-2-4-6(5)8-10-9/h1-4H

Upstream product

• 95-51-2 o-chloroaniline 
• 187835-89-8 Trichloro-methanesulfinic acid (2-chloro-phenyl)-amide 
• 187835-85-4 N-(2-Chloro-phenyl)-S-trichloromethyl-thiohydroxylamine 

Downstream Products

• 2740-81-0 2-chlorophenylisothiocyanate 
• 100170-77-2 2-(2-chloro-phenyl)-1-oxo-4,4-diphenyl-1λ⁴-[1,2]thiazetidin-3-one 
• 105896-40-0 N-(2-chlorophenyl)ethenesulfinamide 
• 1344679-95-3 (1S,4R)-N-(2-chlorophenyl)-4-ethyl-4-phenyl-1,2-thiazetidin-3-one 1-oxide 
• 1344679-96-4 (1R,4S)-N-(2-chlorophenyl)-4-ethyl-4-phenyl-1,2-thiazetidin-3-one 1-oxide 

Relevant articles and documents

N-heterocyclic carbene catalysis: Enantioselective formal [2+2] cycloaddition of ketenes and N-sulfinylanilines

Sultam of swing: Both enantiomers of 1,2-thiazetidin-3-one oxides were obtained in very good yields with excellent enantioselectivities when using N-heterocyclic carbene catalysts (see scheme; M.S.=molecular sieves, TBS=tert-butyldimethylsilyl). The products were easily converted into 3-oxo-β-sultams, α-mercapto amides, and β-mercapto amines through oxidation or reduction. Copyright

Substituted N-aryl alk-1-enesulfinamides: Preparation, properties and conversion into the corresponding indole compounds [1]

Reaction of vinylic organometallic derivatives with N-sulfinyl arenamines 2 affords the title sulfinamides 3. On heating their solutions in selected solvents to 80-124 °C, these sulfinamides are converted into the corresponding indoles 6, probably via a [3.3]-sigmatropic rearrangement to intermediates VIII which undergo an intramolecular carbophilic reaction of the nitrogen atom with the neighboring sulfine group, followed by elimination of HSOH. The triethyloxonium tetrafluoroborate- or boron trifluoride etherate catalyzed conversion 3 → 6 can be carried out at a much lower temperature. Elsevier,.