5466-67-1

Basic information

• Product Name: 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile
• Synonyms: Pyrazolo[1,5-a]pyrimidine-2-acetonitrile, 3-cyano-5,7-dimethyl-
• CAS NO: 5466-67-1
• Molecular Formula: C₁₁H₉N₅
• Molecular Weight: 211.2227
• Mol File: 5466-67-1.mol
• Article Data: 2

Chemical Properties

• Density: 1.28g/cm³
• Refractive Index: 1.671
• CAS DataBase Reference: 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile(5466-67-1)
• EPA Substance Registry System: 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile(5466-67-1)

Safety Data

• Hazardous Substances Data: 5466-67-1(Hazardous Substances Data)

Usage

General Description

The chemical 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile is a heterocyclic compound with a pyrazolo[1,5-a]pyrimidine core. It contains a cyanomethyl group and two methyl groups, and has a carbonitrile functional group. 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile may have potential applications in medicinal chemistry or material science due to its unique structure and chemical properties. Further research and investigation may be necessary to fully understand and utilize the potential of this chemical.

Upstream product

• 64-17-5 ethanol 
• 917-58-8 potassium ethoxide 
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• 123-54-6 acetylacetone 

Relevant articles and documents

Pyrazolo[1,5-a]Pyrimidine Derivative as Precursor for Some Novel Pyrazolo[1,5-a]Pyrimidines and Tetraheterocyclic Compounds

The 2-(cyanomethyl)-5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonitrile 3 reacted with phenyl isothiocyanate to afford the respective thioanilide derivative 4 that is a novel compound that has been unreported hitherto. The latter was used as a precursor to synthesize several novel polyheterocyclic compounds 9, 12, 15, and 19. Treatment of the enamine derivative of compound 3 with each of hydrazine hydrate and hydroxylamine hydrochloride yielded the tetraheterocyclic compounds 22 and 23, respectively. The structures of all the newly synthesized compounds were confirmed on basis of their elemental, spectral data, and plausible mechanism has been postulated to account for their formation. X-ray crystallography was carried out as a further evidence for the structure of the isolated product 19.