5467-62-9Relevant articles and documents
QUINOLINE DERIVATIVE HAVING SEROTONIN-3 RECEPTOR ANTAGONIZING ACTIVITY
-
, (2008/06/13)
Quinoline derivatives represented by formula (I): STR1 wherein A-B-D represents--C(COO--Y)=CH--C(OR)= (wherein Y represents 8-methyl-8-azabicyclo[3.2.1]oct-3-yl group and R represents alkyl) or--C(OH)=C(COX--Y)--CH= (wherein X represents--O--or--NH--; and Y has the same meaning as described above), or a pharmaceutically acceptable salt thereof, possess potent 5HT 3 antagonizing activity and are useful as antiemetic agents.