54672-45-6

Basic information

• Product Name: 1,1-Difluor-2-m-chlorphenylcyclopropan
• Synonyms: 1,1-Difluor-2-m-chlorphenylcyclopropan
• CAS NO: 54672-45-6
• Molecular Weight: 188.604
• Mol File: 54672-45-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,1-Difluor-2-m-chlorphenylcyclopropan(CAS DataBase Reference)
• NIST Chemistry Reference: 1,1-Difluor-2-m-chlorphenylcyclopropan(54672-45-6)
• EPA Substance Registry System: 1,1-Difluor-2-m-chlorphenylcyclopropan(54672-45-6)

Safety Data

• Hazardous Substances Data: 54672-45-6(Hazardous Substances Data)

Upstream product

• 2039-85-2 3-Chlorostyrene 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 24925-18-6 phenyl(trifluoromethyl)mercury 

Relevant articles and documents

Palladium-Catalyzed Ring-Opening Coupling of gem-Difluorocyclopropanes for the Construction of 2-Fluoroallylic Sulfones

A Pd-catalyzed ring-opening sulfonylation of gem-difluorocyclopropanes is reported. This protocol involves C-C bond cleavage, β-F elimination, and allylic coupling to form corresponding 2-fluoroallylic sulfones efficiently with Z-selectivity. Different substrates bearing diverse functional groups are tolerated. Moreover, this method is successfully used for the late-stage derivation of several bioactive molecules.