54684-83-2
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Basic information
- Product Name: POLYGUANYLIC ACID (5') POTASSIUM SALT
- Synonyms: POLY[G] POTASSIUM SALT;POLYGUANYLIC ACID (5') POTASSIUM SALT;POLYGUANYLIC ACID POTASSIUM SALT;polyguanylic acid (5') potassium
- CAS NO:54684-83-2
- Molecular Formula: C10H14N5O8P
- Molecular Weight: 363.22
- EINECS: N/A
- Product Categories: N/A
- Mol File: 54684-83-2.mol
- Article Data: 0
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /lyophilized powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: POLYGUANYLIC ACID (5') POTASSIUM SALT(CAS DataBase Reference)
- NIST Chemistry Reference: POLYGUANYLIC ACID (5') POTASSIUM SALT(54684-83-2)
- EPA Substance Registry System: POLYGUANYLIC ACID (5') POTASSIUM SALT(54684-83-2)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- F: 3-10-21
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 54684-83-2(Hazardous Substances Data)
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54684-83-2 Usage
Description
Polyguanylic acid (5') potassium salt, also known as poly(G), is a synthetic polynucleotide composed of a long chain of guanine bases linked by phosphodiester bonds. It exhibits unique properties and has been widely studied for its potential applications in various fields.Uses
Used in Biomedical Research:Polyguanylic acid (5') potassium salt is used as a ligand for surface neuropilin-1 (NRP1) for internalization studies. This allows researchers to investigate the interaction between the ligand and the receptor, providing insights into the underlying mechanisms of cellular processes.
Used in Chemical Synthesis:
Polyguanylic acid (5') potassium salt is used for intercalation studies with trisubstituted and disubstituted triazole-linked phenyl derivatives CL41, CL42, and CL2r50 using the voltammetry method. This helps in understanding the binding properties and interactions between the polynucleotide and various chemical compounds.
Used in Molecular Biology:
Polyguanylic acid (5') potassium salt is used as a synthetic polynucleotide for agarose gel electrophoresis analysis. This technique is essential for the separation and identification of DNA fragments, enabling researchers to study genetic variations and analyze DNA samples.
Biochem/physiol Actions
Polyguanylic acid acts as a ligand for scavenger receptor and reduces the surface expression neuropilin-1 in endothelial cells.Check Digit Verification of cas no
The CAS Registry Mumber 54684-83-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,6,8 and 4 respectively; the second part has 2 digits, 8 and 3 respectively.Calculate Digit Verification of CAS Registry Number 54684-83:
(7*5)+(6*4)+(5*6)+(4*8)+(3*4)+(2*8)+(1*3)=152
152 % 10 = 2
So 54684-83-2 is a valid CAS Registry Number.
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POLYGUANYLIC ACID (5') POTASSIUM SALT
