54714-44-2

Basic information

• Product Name: 2-bromo-6,7-dimethoxy-3,4-dihydronaphthalen-1(2H)-one
• CAS NO: 54714-44-2
• Molecular Formula: C₁₂H₁₃BrO₃
• Molecular Weight: 285.1338
• Mol File: 54714-44-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 400.1°C at 760 mmHg
• Flash Point: 195.8°C
• Density: 1.461g/cm³
• Vapor Pressure: 1.31E-06mmHg at 25°C
• Refractive Index: 1.573
• CAS DataBase Reference: 2-bromo-6,7-dimethoxy-3,4-dihydronaphthalen-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-bromo-6,7-dimethoxy-3,4-dihydronaphthalen-1(2H)-one(54714-44-2)
• EPA Substance Registry System: 2-bromo-6,7-dimethoxy-3,4-dihydronaphthalen-1(2H)-one(54714-44-2)

Safety Data

• Hazardous Substances Data: 54714-44-2(Hazardous Substances Data)

Upstream product

• 13575-75-2 6,7-dimethoxy-1-oxo-1,2,3,4-tetrahydronaphthalene 
• 91-16-7 1,2-dimethoxybenzene 
• 5333-34-6 3-(3,4-dimethoxybenzoyl)propionic acid 

Downstream Products

• 57595-88-7 allyl-(7,8-dimethoxy-4,5-dihydro-naphtho[1,2-d]thiazol-2-yl)-amine 
• 57595-89-8 7,8-dimethoxy-2-methyl-4,5-dihydro-naphtho[1,2-d]thiazole 
• 57595-86-5 7,8-dimethoxy-4,5-dihydro-naphtho[1,2-d]thiazol-2-ylamine 
• 57595-87-6 (7,8-dimethoxy-4,5-dihydro-naphtho[1,2-d]thiazol-2-yl)-phenyl-amine 
• 1021529-09-8 C₂₃H₂₈N₂O₃ 
• 1354964-51-4 (E)-2-(2-(7,8-dimethoxy-4,5-dihydronaphtho[1,2-d]thiazol-2-yl)hydrazono)-3-(2-nitrophenyl)propanoic acid 
• 1354964-52-5 (Z)-2-(2-(7,8-dimethoxy-4,5-dihydronaphtho[1,2-d]thiazol-2-yl)hydrazono)-3-(2-nitrophenyl) propanoic acid 

Relevant articles and documents

COMPOUNDS FOR THE INHIBITION OF CELLULAR PROLIFERATION

Compositions and methods for inhibiting translation are provided. Compositions, methods and kits for treating (1) cellular proliferative disorders, (2) non-proliferative, degenerative disorders, (3) viral infections, (4) disorders associated with viral infections, and/or (5) non-proliferative metabolic disorders such as type II diabetes where inhibition of translation initiation is beneficial using the compounds disclosed herein.

Facile transformation of 1-methoxynaphthalenes to octahydrophenanthrenes. Application to the total synthesis of (±)-sempervirol methyl ether, (±)-sugiol methyl ether, (±)-nimbiol methyl ether, and (±)-nimbidiol dimethyl ether

An efficient general method has been developed for the synthesis of the tricyclic aromatic ketones 4, 12, 13 and 14 from the 1-methoxynaphthalenes 8, 9, 10 and 11 respectively. The transformations of the ketones 4, 12, 13 and 14 into the diterpene ethers (±)-sempervirol methyl ether (7), (±)-sugiol methyl ether (15), (±)-nimbiol methyl ether (16), and (±)-nimbidiol dimethyl ether (17) have been successfully accomplished involving reductive methylation in liquid ammonia as the key reaction.

Substituted indeno, naphtho and cyclohepta pyrazoles

Substituted indeno [1,2-c] pyrazoles, naphtho [1,2-c] pyrazoles and benzo [6,7] cyclohepta [1,2-c] pyrazoles e.g., 3-(2,3-dimethoxyphenyl)-4H-indeno[1,2-c] pyrazole and 4,5-dihydro-3-(4-pyridyl)-2H-naphtho[1,2-c] pyrazole, are useful as non-estrogenic anti-fertility agents and antihypertensive agents.