54757-04-9

Basic information

• Product Name: Phosphonium, triphenyl[(2,4,6-trimethylphenyl)methyl]-, chloride
• CAS NO: 54757-04-9
• Molecular Formula: C28H28P.Cl
• Molecular Weight: 430.957
• Mol File: 54757-04-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Phosphonium, triphenyl[(2,4,6-trimethylphenyl)methyl]-, chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonium, triphenyl[(2,4,6-trimethylphenyl)methyl]-, chloride(54757-04-9)
• EPA Substance Registry System: Phosphonium, triphenyl[(2,4,6-trimethylphenyl)methyl]-, chloride(54757-04-9)

Safety Data

• Hazardous Substances Data: 54757-04-9(Hazardous Substances Data)

Upstream product

• 1585-16-6 2-chloromethyl-1,3,5-trimethylbenzene 
• 603-35-0 triphenylphosphine 

Downstream Products

• 92345-75-0 (2,4,6-trimethylbenzylidene)triphenylphosphorane 
• 92345-79-4 1-(1-phenyl-2-mesitylethenyl)-4-(2-mesitylethenyl)benzene 
• 115591-94-1 1-Phenyl-5-<(E)-phenylmethylen>-2-(2,4,6-trimethylphenyl)spiro<2.4>heptan-4-on 
• 149791-59-3 (7'E)-7'-(2,4,6-trimethylphenyl)-7'-apo-β-carotene 

Relevant articles and documents

Chemical Consequences of Single-Electron Oxidation of Phenylmesityldiazoethane

Both thermolysis and photolysis of 1-phenyl-2-mesityldiazoethane (PMDE) lead exclusively to products derived from facile hydrogen or mesityl migration subsequent to, or concurrent with, loss of N2.No detectable amounts of ketazine or any dimeric hydrocarbons are formed in these reactions -a result that is attributable to the steric hindrance about the diazo carbon in PMDE.Quite in contrast, the one-electron oxidation of this diazoalkane yields no monomeric products by simple hydrogen or mesityl migration; instead, ketazine and dimeric products are formed by two distinct paths.Dimerization of diazo radical cations followed by competing secondary reactions of the resulting dication is the favored path according for the major products.In a very much slower reaction, PMDE+. attacks neutral PMDE to yield ketazine.

NITROGENOUS HETEROCYCLIC DERIVATIVE HAVING 2,6-DISUBSTITUTED STYRYL

The invention provides a novel nitrogen-containing heterocyclic derivative having 2,6-disubstituted styryl and a pharmaceutically acceptable salt thereof, and a pharmaceutical composition comprising the nitrogen-containing heterocyclic derivative and a pharmaceutically acceptable salt thereof, in particular, a pharmaceutical composition effective as a sodium channel inhibitor, having an excellent analgesic action especially on neuropathic pain with minimized side effects.