54788-35-1 Usage
Description
1-Aminoethylphosphonic acid diethyl, also known as Diethyl (1-Aminoethyl)phosphonate, is an organic compound with the chemical formula (C2H5O)2P(O)NHCH2CH2OH. It is a colorless liquid with a slight odor and is soluble in water and organic solvents. 1-Aminoethylphosphonic acid diethyl is known for its unique chemical properties and potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
1-Aminoethylphosphonic acid diethyl is used as a reagent in the preparation of heterocyclic phosphopeptides, which are important for the development of new drugs and therapeutic agents. These phosphopeptides have potential applications in the treatment of various diseases, including cancer, neurological disorders, and inflammatory conditions.
Used in Enzyme Research:
1-Aminoethylphosphonic acid diethyl is used in the study of the activity of Candida antarctica lipase B (CALB), an enzyme with potential applications in various industries, such as food, pharmaceutical, and biofuel production. By understanding the effects of this compound on CALB, researchers can gain insights into enzyme function and develop more efficient biocatalysts.
Used in Adhesive Industry:
1-Aminoethylphosphonic acid diethyl is used as a component in the preparation of self-adhesive labels. Its unique chemical properties allow it to improve the adhesion properties of the labels, making them more effective and durable. This application is particularly useful in industries that require high-quality labeling, such as packaging, logistics, and product identification.
Check Digit Verification of cas no
The CAS Registry Mumber 54788-35-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,7,8 and 8 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 54788-35:
(7*5)+(6*4)+(5*7)+(4*8)+(3*8)+(2*3)+(1*5)=161
161 % 10 = 1
So 54788-35-1 is a valid CAS Registry Number.
54788-35-1Relevant articles and documents
The Facile Synthesis of O,O-Dialkyl 1-Aminoalkanephosphonates
Green, Donovan,Patel, Geeta,Elgendy, Said,Baban, Jehan A.,Claeson, Goeran,et al.
, p. 6917 - 6920 (1993)
O,O-Dialkyl 1-hydroxyiminoalkanephosphonates 1, may be conveniently reduced to O,O-dialkyl 1-aminoalkanephosphonates 2, at ambient temperature by application of lithium borohydride/trimethylsilyl chloride
Intensified Continuous Flow Michaelis-Arbuzov Rearrangement toward Alkyl Phosphonates
Monbaliu, Jean-Christophe M.,Toupy, Thomas
supporting information, p. 467 - 478 (2022/02/25)
Herein is described the development of an intensified continuous flow process for the preparation of a library of alkyl phosphonates through a Michaelis-Arbuzov rearrangement. A careful process optimization and thorough analysis of the competitive reactions led to a very attractive protocol with unprecedented productivities (up to 4.97 kg of material per day) and a low environmental footprint with the absence of solvent, additives, catalysts, and waste. In-line low-field 31P NMR monitoring was conveniently implemented for rapid optimization and process monitoring. Two key alkyl phosphonate intermediates were also assessed for the unprecedented diazene dicarboxylate-mediated electrophilic amination under continuous flow conditions toward the α-aminophosphonic acid derivatives of Pphenylalanine and Palanine, bioisosters of the natural amino acids phenylalanine and alanine, respectively.
Surface-mediated solid phase reactions: A simple and new method for the synthesis of α-aminophosphonates under solvent-free conditions
Kaboudin, Babak
, p. 880 - 881 (2007/10/03)
Alumina-supported ammonium formate was found to be an efficient reagent for the synthesis of 1-aminophosphonates from aldehydes and diethyl phosphite. This method is an easy, rapid and high-yielding reaction for the synthesis of 1-aminophosphonates.
