54794-73-9Relevant articles and documents
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Jacobson
, p. 100,102 (1951)
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USE OF ENDOCANNABINOID-LIKE COMPOUNDS FOR TREATING CNS DEGENERATIVE DISORDERS
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Paragraph 0102-0104, (2017/09/12)
no abstract published
Mass spectral characterization of fatty acid amides from alfalfa trichomes and their deterrence against the potato leafhopper
Ranger, Christopher M.,Winter, Rudolph E.K.,Rottinghaus, George E.,Backus, Elaine A.,Johnson, David W.
, p. 529 - 541 (2008/02/03)
A homologous series of N-(3-methylbutyl)amides of normal saturated C 14, C15, C16, C17 and C18 fatty acids were identified as major components of glandular trichome extracts from Medicago sativa G98A, an alfalfa genotype resistant to the potato leafhopper, Empoasca fabae. A second homologous series of N-(2-methylpropyl) amides of C14 through C18 normal fatty acids were minor components. Saturated free fatty acids C12, C13, C 14, C15, C16, C17 and C18 were present in trace amounts, as was the N-(3-methylbutyl)amide of linoleic acid (C18:2). N-(3-methylbutyl)amides and N-(2-methylpropyl)amides of C14 through C18 fatty acids, along with the N-(3-methylbutyl)amide of linoleic acid, were synthesized and bioassayed for leafhopper deterrence by applying the compounds to the surface of a sachet containing an artificial diet. Leafhoppers were then offered a two-way choice between diet surfaces treated with the synthetic amides or an untreated control. N-(3-methylbutyl)amides and N-(2-methylpropyl)amides of C14 through C18 fatty acids did not deter leafhopper settling in a dose-dependent fashion. In contrast, when tested singly, N-(3-methylbutyl)amide of linoleic acid exhibited dose-dependent deterrence against leafhopper settling. Fatty acid amides localized in alfalfa glandular trichomes likely contribute to leafhopper resistance.
