54811-41-5Relevant articles and documents
Rhodium-Catalyzed ortho-Arylation of (Hetero)aromatic Acids
Weber, Philip,Rank, Christian K.,Yalcinkaya, Enis,Dyga, Marco,van Lingen, Tim,Schmid, Rochus,Patureau, Frederic W.,Goo?en, Lukas J.
supporting information, p. 3925 - 3929 (2019/07/15)
Rhodium acetate effectively promotes the carboxylate-directed ortho-arylation of (hetero)aromatic carboxylates with aryl bromides. The main advantage of this phosphine-free, redox-neutral method arises from its efficiency in assembling biologically meaningful electron-rich arylpyridines, which are problematic substrates in known C?H arylations using Pd, Ru, and Ir catalysts. (Figure presented.).
