54813-77-3

Basic information

• Product Name: N-ETHYL-N-ISOPROPYLANILINE
• Synonyms: N-ETHYL-N-ISOPROPYLANILINE
• CAS NO: 54813-77-3
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.26
• Product Categories: Amines;C11 to C38;Nitrogen Compounds;Building Blocks;C10 to C11;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 54813-77-3.mol
• Article Data: 7

Chemical Properties

• Melting Point: 46.25°C (estimate)
• Boiling Point: 223-225 °C(lit.)
• Flash Point: 194 °F
• Appearance: /
• Density: 0.926 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0771mmHg at 25°C
• Refractive Index: n20/D 1.534(lit.)
• PKA: 7.38±0.20(Predicted)
• CAS DataBase Reference: N-ETHYL-N-ISOPROPYLANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-ETHYL-N-ISOPROPYLANILINE(54813-77-3)
• EPA Substance Registry System: N-ETHYL-N-ISOPROPYLANILINE(54813-77-3)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 54813-77-3(Hazardous Substances Data)

Usage

General Description

N-ETHYL-N-ISOPROPYLANILINE is an organic compound with the chemical formula C11H17N. It is a clear, colorless to pale yellow liquid with a strong amine odor. This chemical is commonly used as an intermediate in the synthesis of dyes, pharmaceuticals, and other organic compounds. N-ETHYL-N-ISOPROPYLANILINE is also used as a corrosion inhibitor in cutting fluids, as an antioxidant in rubber and plastic products, and as a stabilizer for gasoline and jet fuels. It is important to handle this substance with caution, as it can be harmful if ingested, inhaled, or absorbed through the skin, and it may cause irritation to the eyes and respiratory tract. Proper safety measures and personal protective equipment should be used when working with N-ETHYL-N-ISOPROPYLANILINE.

InChI:InChI=1/C11H17N/c1-4-12(10(2)3)11-8-6-5-7-9-11/h5-10H,4H2,1-3H3

Upstream product

• 75-30-9 2-iodo-propane 
• 103-69-5 N-ethyl-N-phenylamine 
• 5461-51-8 N-isopropyl-N-phenyl-acetamide 
• 80041-89-0 isopropylboronic acid 
• 98-95-3 nitrobenzene 
• 122-52-1 triethyl phosphite 
• 67-64-1 acetone 

Downstream Products

• 20914-20-9 isopropyl-phenyl-carbamonitrile 
• 19961-27-4 N-isopropylethylamine 
• 35616-26-3 N-isopropyl-N,N-dimethyl-anilinium; iodide 
• 2893-61-0 2-(ethyl-isopropyl-amino)-ethanol 
• 36648-40-5 1-ethyl-3-phenyl-1H-indole 
• 1034366-68-1 1-isopropyl-3-phenyl-1H-indole 
• 1380105-27-0 C₂₉H₃₈N₂ 

Relevant articles and documents

Reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3as a reductant

Herein, we report the first example of efficient reductive amination of ketones/aldehydes with amines using BH3N(C2H5)3 as a catalyst and a reductant under mild conditions, affording various tertiary and secondary amines in excellent yields. A mechanistic study indicates that BH3N(C2H5)3 plays a dual function role of promoting imine and iminium formation and serving as a reductant in reductive amination. This journal is

Sodium Triethylborohydride-Catalyzed Controlled Reduction of Unactivated Amides to Secondary or Tertiary Amines

The first transition-metal-free catalytic protocol for controlled reduction of amide functions using cheap and bench-stable hydrosilanes as reducing agents has been established. By altering the hydrosilane and solvent, the new method enables the selective cleavage of unactivated C-O bonds in amides and allows the C-N bonds to selectively break via the deacylated cleavage. Overall, this novel process may offer a versatile alternative to current methodologies employing stoichiometric metal systems for the controlled reduction of carboxamides.

Method for selective reducing reaction of tertiary aryl amide and borane

The present invention relates to a method for a selective reducing reaction of a tertiary aryl amide and borane. A tertiary amine product is prepared by the reducing reaction of a tertiary aryl amidederivative and a cheap and easily available organoboron reagent under mild conditions under the convenient catalysis of a non-transition metal compound sodium triethylborohydride used as a catalyst for the first time. Compared with traditional methods, the method of the method generally has the advantages of wide universality of a substrate, low cost and easy availability of the catalyst, and simplicity in reaction operation. The selective reducing reaction of the tertiary aryl amide compound and the organoboron reagent under the catalysis of the transition metal catalyst is realized for the first time, and a brand new "green" reaction strategy is provided for the laboratory preparation or industrial production of tertiary arylamine products.