54818-84-7

Basic information

• Product Name: N-(5-Chloro-pyridin-2-yl)-4-Methyl-benzenesulfonaMide
• Synonyms: N-(5-Chloro-pyridin-2-yl)-4-Methyl-benzenesulfonaMide
• CAS NO: 54818-84-7
• Molecular Formula: C₁₂H₁₁ClN₂O₂S
• Molecular Weight: 282.74594
• EINECS: -0
• Mol File: 54818-84-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(5-Chloro-pyridin-2-yl)-4-Methyl-benzenesulfonaMide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-Chloro-pyridin-2-yl)-4-Methyl-benzenesulfonaMide(54818-84-7)
• EPA Substance Registry System: N-(5-Chloro-pyridin-2-yl)-4-Methyl-benzenesulfonaMide(54818-84-7)

Safety Data

• Hazardous Substances Data: 54818-84-7(Hazardous Substances Data)

Upstream product

• 20511-12-0 2-amino-5-iodopyridine 
• 98-59-9 p-toluenesulfonyl chloride 
• 1072-98-6 5-chloro-2-pyridylamine 

Downstream Products

• 209971-45-9 2-{5-Chloro-2-[(E)-toluene-4-sulfonylimino]-2H-pyridin-1-yl}-acetamide 

Relevant articles and documents

6-Substituted 2-(N-trifluoroacetylamino)imidazopyridines induce cell cycle arrest and apoptosis in SK-LU-1 human cancer cell line

A series of 6-substituted 2-(N-trifluoroacetylamino)imidazopyridines have been synthesized and their bioactivities were evaluated. Compounds 6a, 6c, and 11a were the most active compounds with modest cytotoxic activity against six human cancer cell lines U251 (glioma), PC-3 (prostate), K-562 (leukemia), HCT-15 (colon), MCF7 (breast) and SK-LU-1 (lung). The cell cycle analysis showed that compounds 6a, 6c, and 11a induce a G2/M phase cell cycle arrest on SK-LU-1 cell line where inhibition of CDK-1 and CDK-2 may be implicated.