54819-72-6

Basic information

• Product Name: N-(3-chlorophenyl)-2-(2-imino-4-oxothiazolidin-5-yl)acetamide
• Synonyms: N-(3-chlorophenyl)-2-(2-imino-4-oxothiazolidin-5-yl)acetamide;N-(3-chlorophenyl)-2-(2-imino-4-oxo-1,3-thiazolidin-5-yl)acetamide
• CAS NO: 54819-72-6
• Molecular Formula: C₁₁H₁₀ClN₃O₂S
• Molecular Weight: 283.734
• Mol File: 54819-72-6.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(3-chlorophenyl)-2-(2-imino-4-oxothiazolidin-5-yl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-chlorophenyl)-2-(2-imino-4-oxothiazolidin-5-yl)acetamide(54819-72-6)
• EPA Substance Registry System: N-(3-chlorophenyl)-2-(2-imino-4-oxothiazolidin-5-yl)acetamide(54819-72-6)

Safety Data

• Hazardous Substances Data: 54819-72-6(Hazardous Substances Data)

Upstream product

• 1204-35-9 N-(3-chlorophenyl)maleimide 
• 17356-08-0 thiourea 
• 36847-88-8 C₁₀H₈ClNO₃ 

Relevant articles and documents

Identification of iminooxothiazolidines as secreted frizzled related protein-1 inhibitors

Secreted frizzled related protein-1 (sFRP-1) inhibitors have the potential to be used for the treatment of osteoporosis or other bone related disorders, since the level of sFRP-1 affects osteoblast apoptosis and proliferation. From high throughput screening, we have identified a class of iminooxothiazolidines as sFRP-1 inhibitors. Structure-activity relationships were established for various regions of the scaffold along with the biochemical characterization of this class to probe selectivity, binding and ex vivo activity.