54848-86-1

Basic information

• Product Name: chloromethyl(2-methylphenyl)dimethylchlorosilane
• Synonyms: chloromethyl(2-methylphenyl)dimethylchlorosilane
• CAS NO: 54848-86-1
• Molecular Weight: 198.768
• Mol File: 54848-86-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: chloromethyl(2-methylphenyl)dimethylchlorosilane(CAS DataBase Reference)
• NIST Chemistry Reference: chloromethyl(2-methylphenyl)dimethylchlorosilane(54848-86-1)
• EPA Substance Registry System: chloromethyl(2-methylphenyl)dimethylchlorosilane(54848-86-1)

Safety Data

• Hazardous Substances Data: 54848-86-1(Hazardous Substances Data)

Upstream product

• 1719-57-9 Chloro(chloromethyl)dimethylsilane 
• 95-46-5 2-methylphenyl bromide 
• 932-31-0 ortho-tolylmagnesium bromide 

Downstream Products

• 180071-77-6 (E)-ethyl-3-<((2-methylphenyl)dimethylsilyl)methoxy>-propenoate 
• 54848-87-2 (o-bromomethylphenyl)dimethylchloromethylsilane 
• 180071-78-7 Methanesulfonic acid (E)-2-{3-[(dimethyl-o-tolyl-silanyl)-methoxy]-benzyl}-8,8-dimethyl-non-4-en-6-ynyl ester 
• 1027646-67-8 (E)-2-{3-[(Dimethyl-o-tolyl-silanyl)-methoxy]-benzyl}-8,8-dimethyl-non-4-en-6-ynoic acid ethyl ester 
• 180071-76-5 2-<3-<((2-methylphenyl)dimethylsilyl)methoxy>benzyl>-8,8-dimethyl-non-4-ene-6-ynol 
• 180071-79-8 ethyl-3-<((2-methylphenyl)dimethylsilyl)methoxy>propinoate 
• 176100-05-3 [(Dimethyl-o-tolyl-silanyl)-methyl]-(3-ethylaminomethyl-phenyl)-amine 
• 176100-04-2 3-{[(Dimethyl-o-tolyl-silanyl)-methyl]-amino}-benzaldehyde 
• 176100-03-1 N-(3-Cyano-phenyl)-N-[(dimethyl-o-tolyl-silanyl)-methyl]-2,2,2-trifluoro-acetamide 

Relevant articles and documents

A convergent and straightforward synthetic method to prepare deaza-analogs of squalene epoxidase inhibitors

A general route to deaza-analogs of squalene epoxidase inhibitors of general formula A is described using a very convergent synthetic scheme illustrated by the preparation of compound 2b. A Heck reaction, and an enolate condensation with an appropriate electrophile are the key steps of the expedient elaboration of 2b or analogs.