54851-35-3

Basic information

• Product Name: 5-amino-6-chloro-1H-pyrimidine-4-thione
• Synonyms: 5-amino-6-chloro-1H-pyrimidine-4-thione;5-aMino-6-chloropyriMidine-4-thiol
• CAS NO: 54851-35-3
• Molecular Formula: C₄H₄ClN₃S
• Molecular Weight: 161.61
• Mol File: 54851-35-3.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 213.6°C at 760 mmHg
• Flash Point: 83°C
• Appearance: /
• Density: 1.74g/cm³
• Vapor Pressure: 0.163mmHg at 25°C
• Refractive Index: 1.769
• CAS DataBase Reference: 5-amino-6-chloro-1H-pyrimidine-4-thione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-amino-6-chloro-1H-pyrimidine-4-thione(54851-35-3)
• EPA Substance Registry System: 5-amino-6-chloro-1H-pyrimidine-4-thione(54851-35-3)

Safety Data

• Hazardous Substances Data: 54851-35-3(Hazardous Substances Data)

Usage

General Description

5-amino-6-chloro-1H-pyrimidine-4-thione is a chemical compound with a molecular formula C4H3ClN3S. It is a pyrimidine derivative with an amino group at the 5th carbon and a chlorine atom at the 6th carbon. The presence of the thione group at the 4th carbon gives this compound its unique properties. It is commonly used in organic synthesis and pharmaceutical research for the development of new drugs. 5-amino-6-chloro-1H-pyrimidine-4-thione has shown potential as an antiviral and antitumor agent, making it a key focus in medicinal chemistry. Its versatile structure allows for the modification of its properties to suit specific applications in various fields, making it a valuable building block in chemical research.

InChI:InChI=1/C4H4ClN3S/c5-3-2(6)4(9)8-1-7-3/h1H,6H2,(H,7,8,9)

Upstream product

• 5413-85-4 5-amino-4,6-dichloropyridimine 

Downstream Products

• 57417-53-5 5-amino-3H-pyrimidine-4-thione 
• 54660-78-5 5-amino-4-chloropyrimidine 
• 32605-32-6 4-chloro-6-(4-nitro-phenyl)-6,7-dihydro-5H-pyrimido[4,5-b][1,4]thiazin-6-ol 
• 13316-12-6 7-chloro[1,3]thiazolo[5,4-d]pyrimidine 
• 19084-50-5 4-chloro-6-phenyl-7H-pyrimido[4,5-b][1,4]thiazine 
• 19084-49-2 6-(4-bromo-phenyl)-4-chloro-7H-pyrimido[4,5-b][1,4]thiazine 
• 19084-41-4 4-chloro-6-(2,5-dichloro-phenyl)-6,7-dihydro-5H-pyrimido[4,5-b][1,4]thiazin-6-ol 

Relevant articles and documents

FERROPORTIN INHIBITORS AND METHODS OF USE

The subject matter described herein is directed to Ferroportin inhibitor compounds of Formula I and pharmaceutical salts thereof, methods of preparing the compounds, pharmaceutical compositions comprising the compounds and methods of administering the compounds for prophylaxis and/or treatment of diseases caused by a lack of hepcidin or iron metabolism disorders, particularly iron overload states, such as thalassemia, sickle cell disease and hemochromatosis.

PIPERIDINE SUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES WITH INHIBITORY ACTIVITY ON THE REPLICATION OF THE RESPIRATORY SYNCYTIAL VIRUS (RSV)

The invention concerns novel substituted bicyclic pyrazolo pyrimidine compounds of formula (I) having antiviral activity, in particular, having an inhibitory activity on the replication of the respiratory syncytial virus (RSV). The invention further conce

HETEROCYCLIC COMPOUNDS AND USES THEREOF

Compounds and pharmaceutical compositions of formulae (I), (XI) and (XII) as PI3 kinase modulators and their use in the treatment of diseases such as cancer.