54863-44-4

Basic information

• Product Name: Octanenitrile, 8-bromo-
• CAS NO: 54863-44-4
• Molecular Formula: C8H14BrN
• Molecular Weight: 204.11
• Mol File: 54863-44-4.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Octanenitrile, 8-bromo-(CAS DataBase Reference)
• NIST Chemistry Reference: Octanenitrile, 8-bromo-(54863-44-4)
• EPA Substance Registry System: Octanenitrile, 8-bromo-(54863-44-4)

Safety Data

• Hazardous Substances Data: 54863-44-4(Hazardous Substances Data)

Usage

General Description

Octanenitrile, 8-bromo- is a chemical compound with the molecular formula C8H16BrN. It is also known as 8-bromooctanenitrile or 8-cyanooctyl bromide. It is a colorless to pale yellow liquid with a faint, sweet odor. This chemical is used in the synthesis of various organic compounds, including pharmaceuticals and agrochemicals. It is also used as an intermediate in the manufacture of other chemicals. Octanenitrile, 8-bromo- is flammable and may be harmful if swallowed, inhaled, or absorbed through the skin, so proper handling and storage are essential to ensure safety.

Upstream product

• 73674-09-6 8-bromo-n-octanoyl chloride 
• 773837-37-9 sodium cyanide 
• 4549-31-9 1,7-dibromoheptane 
• 88785-06-2 8-bromooctanamide 
• 17696-11-6 8-bromooctanoic acid 

Downstream Products

• 332848-57-4 C₈⁽¹⁴⁾CH₁₆O₄ 
• 1363409-81-7 C₈⁽¹¹⁾CH₁₄N₂ 
• 1642-49-5 dec-9-ynoic acid 
• 88785-00-6 1-Brom-7-(2,4,10-trioxatricyclo<3.3.1.1^3,7>dec-3-yl)heptan 
• 220015-84-9 (E)-Octadec-9-enedioic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester 
• 220015-74-7 (Z)-Octadec-9-enedioic acid bis-(2,5-dioxo-pyrrolidin-1-yl) ester 

Relevant articles and documents

Electrical conductivity and glass formation in nitrile-functionalized pyrrolidinium bis(trifluoromethylsulfonyl)imide ionic liquids: Chain length and odd-even effects of the alkyl spacer between the pyrrolidinium ring and the nitrile group

The electrical conductivity of a series of pyrrolidinium bis(trifluoromethylsulfonyl)imide ionic liquids, functionalized with a nitrile (cyano) group at the end of an alkyl chain attached to the cation, was studied in the temperature range between 173 K and 393 K. The glass formation of the ionic liquids is influenced by the length of the alkyl spacer separating the nitrile function from the pyrrolidinium ring. The electrical conductivity and the viscosity do not show a monotonic dependence on the alkyl spacer length, but rather an odd-even effect. An explanation for this behavior is given, including the potential energy landscape picture for the glass transition. This journal is the Partner Organisations 2014.

Rapid radiosynthesis of [11C] and [14C]azelaic, suberic, and sebacic acids for in vivo mechanistic studies of systemic acquired resistance in plants

A recent report that the aliphatic dicarboxylic acid, azelaic acid (1,9-nonanedioic acid) but not related acids, suberic acid (1,8-octanedioic acid) or sebacic (1,10-decanedioic acid) acid induces systemic acquired resistance to invading pathogens in plants stimulated the development of a rapid method for labeling these dicarboxylic acids with 11C and 14C for in vivo mechanistic studies in whole plants. 11C-labeling was performed by reaction of ammonium [ 11C]cyanide with the corresponding bromonitrile precursor followed by hydrolysis with aqueous sodium hydroxide solution. Total synthesis time was 60min. Median decay-corrected radiochemical yield for [11C]azelaic acid was 40% relative to trapped [11C]cyanide, and specific activity was 15GBq/μmol. Yields for [11C]suberic and sebacic acids were similar. The 14C-labeled version of azelaic acid was prepared from potassium [14C]cyanide in 45% overall radiochemical yield. Radiolabeling procedures were verified using 13C-labeling coupled with 13C-NMR and liquid chromatography-mass spectrometry analysis. The 11C and 14C-labeled azelaic acid and related dicarboxylic acids are expected to be of value in understanding the mode-of-action, transport, and fate of this putative signaling molecule in plants.