54898-34-9 Usage
General Description
2'-chlorothymidine is a chemical compound that is structurally similar to thymidine, a key component of DNA. It contains a chloro group attached to the 2' carbon of the thymidine molecule, which can affect its biological activity. 2'-chlorothymidine has been studied for its potential antiviral and antitumor properties, as well as its use in labeling and tracking nucleic acids in research. It has also been investigated for its potential as a diagnostic tool in cancer imaging. The chloro group on the 2' carbon could alter the base pairing properties and overall structure of DNA, which may impact its function in biological processes. Further research is needed to fully understand the effects and potential applications of 2'-chlorothymidine.
Check Digit Verification of cas no
The CAS Registry Mumber 54898-34-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,4,8,9 and 8 respectively; the second part has 2 digits, 3 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 54898-34:
(7*5)+(6*4)+(5*8)+(4*9)+(3*8)+(2*3)+(1*4)=169
169 % 10 = 9
So 54898-34-9 is a valid CAS Registry Number.
InChI:InChI=1/C10H13ClN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)
54898-34-9Relevant articles and documents
Method for preparing β-thymidine
-
Paragraph 0111-0113, (2018/02/04)
The invention relates to a preparation method of beta-thymidine, and specifically discloses a method of preparing beta-thymidine from the formula II compound. The method comprises following steps: subjecting the compound represented as the formula II to carry out dehalogenation reactions, in a hydrogen atmosphere, in the presence of a catalyst, and in a buffer system with a pH value of 6.5 to 8.0, so as to obtain beta-thymidine represented as the formula I, wherein X represents Cl or Br. The dehalogenation reactions are carried out under atmospheric pressure, and the preparation method has the advantages of environment-friendliness, economy, high product yield, good product purity, and suitability for industrial production.