54945-27-6Relevant articles and documents
Improved method for the preparation of macrocyclic diamides
Gryko, Daniel T.,Gryko, Dorota,Jurczak, Janusz
, p. 1310 - 1312 (1999)
Sodium methoxide was found to be an effective catalyst in the reaction of diesters with diamines leading to macrocyclic diamides. The time of reaction was shortened by about 20 times as compared with previous results (to several hours usually). Additionally, yields of desired products were improved by about 2-8 times.
Synthetic and crystallographic studies on pyridinophanes
Gryko, Daniel T.,Piatek, Piotr,Pecak, Agnieszka,Palys, Marcin,Jurczak, Janusz
, p. 7505 - 7516 (1998)
Eight macrocyclic bisamides and tetramides have been synthesized by reaction of dimethyl pyridine-2,6-dicarboxylate 1 with α.ω-diaminoethers in methanol as a solvent. Relationship between structure of an amine used and a ratio of bisamide to tetramide has been investigated. The X-ray structure of macrocyclic amides 8, 9, 14 and linear amide 16 are reported. They show intramolecular hydrogen bond patterns within macrocyclic cavities involving N(Py) ··· NH(amide) and in the cases of 9.14 and 16, neutral molecules of water. Stability constants of selected ligands were measured using voltammetry.
