549534-58-9

Basic information

• Product Name: (2R,4S)-4-Alloc-aMino-1-FMoc-Pyrrolidine-2-carboxylic acid
• Synonyms: (2R,4S)-4-Alloc-aMino-1-FMoc-Pyrrolidine-2-carboxylic acid;(2R,4S)-4-Alloc-aMino-1-FMoc-Pyrrolidine-2-carboxylic acidp;(2R,4S)-1-(((9H-fluoren-9-yl)methoxy)carbonyl)-4-(((allyloxy)carbonyl)amino)pyrrolidine-2-carboxylic acid;-4-Alloc-amino-1-Fmoc-Pyrrolidine-2-carboxylic acid
• CAS NO: 549534-58-9
• Molecular Formula: C24H24N2O6
• Molecular Weight: 436.45716
• Mol File: 549534-58-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 654.5±55.0 °C(Predicted)
• Appearance: /
• Density: 1.37±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 3.77±0.40(Predicted)
• CAS DataBase Reference: (2R,4S)-4-Alloc-aMino-1-FMoc-Pyrrolidine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,4S)-4-Alloc-aMino-1-FMoc-Pyrrolidine-2-carboxylic acid(549534-58-9)
• EPA Substance Registry System: (2R,4S)-4-Alloc-aMino-1-FMoc-Pyrrolidine-2-carboxylic acid(549534-58-9)

Safety Data

• Hazardous Substances Data: 549534-58-9(Hazardous Substances Data)

Usage

General Description

The chemical "(2R,4S)-4-Alloc-amino-1-Fmoc-Pyrrolidine-2-carboxylic acid" is a compound with a pyrrolidine ring structure and an amino acid functionality. The "(2R,4S)" designation indicates the stereochemistry of the molecule, specifically the orientation of the substituents around the chiral centers. The "Alloc" group serves as a protecting group for the amine functionality, while the "Fmoc" group is a common protecting group for the carboxylic acid functionality. (2R,4S)-4-Alloc-amino-1-Fmoc-Pyrrolidine-2-carboxylic acid likely has applications in peptide synthesis and organic chemistry, as its structure suggests it can participate in peptide bond formation and other chemical reactions involving amino acids. Overall, "(2R,4S)-4-Alloc-amino-1-Fmoc-Pyrrolidine-2-carboxylic acid" is a complex molecule with potential utility in the field of chemical synthesis.

Upstream product

• 82911-69-1 N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide 
• 132622-69-6 (2S,4R)-4-amino-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic acid 

Relevant articles and documents

Structure - Activity relationship studies of targeting ligands against breast cancer cells

A series of LXY3 (1) analogues were designed and synthesized. Their binding affinity was demonstrated using MDA-MB-231 breast cancer cells adherence inhibition assay. Further structure-activity relationship was obtained. Analogue 29 was discovered to have 3.5-fold increase of the binding affinity. Fluorescent microscopy and in vivo and ex vivo imaging studies demonstrated that 29 is an efficient in vivo targeting agent against α3 integrin of MDA-MB-231 breast tumor xenograft implant. 2009 American Chemical Society.