54998-75-3

Basic information

• Product Name: methyl(4-nitro-3-(trifluoromethyl)phenyl)sulfane
• Synonyms: methyl(4-nitro-3-(trifluoromethyl)phenyl)sulfane
• CAS NO: 54998-75-3
• Molecular Weight: 237.202
• Mol File: 54998-75-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: methyl(4-nitro-3-(trifluoromethyl)phenyl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: methyl(4-nitro-3-(trifluoromethyl)phenyl)sulfane(54998-75-3)
• EPA Substance Registry System: methyl(4-nitro-3-(trifluoromethyl)phenyl)sulfane(54998-75-3)

Safety Data

• Hazardous Substances Data: 54998-75-3(Hazardous Substances Data)

Upstream product

• 393-09-9 4-fluoro-1-nitro-2-trifluoromethyl-benzene 
• 5188-07-8 sodium thiomethoxide 
• 344-38-7 4-bromo-1-nitro-2-(trifluoromethyl)benzene 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 59920-85-3 4-Methylthio-2-trifluoromethylaniline 
• 54939-66-1 3-Trifluormethyl-4-trifluormethylsulfonyl-anilin 
• 54939-64-9 3-Trifluormethyl-4-nitrophenyl-trifluormethylsulfon 
• 320-39-8 (4-nitro-3-trifluoromethyl-phenyl)-trifluoromethyl sulfide 

Relevant articles and documents

METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION

Mutations in oncogenes and tumor suppressors contribute to the development and progression of cancer. The present disclosure describes compounds and methods to recover wild-type function to p53 mutants. The compounds of the present invention can bind to mutant p53 and restore the ability of the p53 mutant to bind DNA and activate downstream effectors involved in tumor suppression. The disclosed compounds can be used to reduce the progression of cancers that contain a p53 mutation.