55-43-6

Basic information

• Product Name: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE
• Synonyms: dibenzylchlorethylaminehydrochloride;n-(2-chloroethyl)-dibenzylaminhydrochloride;n-(2-chloroethyl)-n-(phenylmethyl)-benzenemethanaminhydrochloride;N,N-DIBENZYLAMINOETHYLCHLORIDE HYDROCHLORIDE;N,N-DIBENZYL-BETA-CHLOROETHYLAMINE HYDROCHLORIDE;N,N'-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE;N,N-DIBENZYL-2-CHLOROETHYLAMINE HYDROCHLORIDE;N-(2-CHLOROETHYL)DIBENZYLAMINE HCL
• CAS NO: 55-43-6
• Molecular Formula: C₁₆H₁₈ClN*ClH
• Molecular Weight: 296.23
• EINECS: 200-234-5
• Product Categories: Amine Salts;Nitrogen Compounds;Organic Building Blocks;Amine Salts;Building Blocks;Chemical Synthesis;Nitrogen Compounds;Organic Building Blocks
• Mol File: 55-43-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: 190-193 °C(lit.)
• Boiling Point: 449.72°C (rough estimate)
• Flash Point: 147.3°C
• Appearance: White to off-white/Crystalline Powder
• Density: 1.1507 (rough estimate)
• Refractive Index: 1.6300 (estimate)
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: almost transparency in Methanol
• Merck: 14,2138
• CAS DataBase Reference: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)
• EPA Substance Registry System: N-(2-CHLOROETHYL)DIBENZYLAMINE HYDROCHLORIDE(55-43-6)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• RTECS: HQ6825000
• HazardClass: IRRITANT
• Hazardous Substances Data: 55-43-6(Hazardous Substances Data)

Usage

Uses

Sympatholytin was used as 5-Hydroxytryptamine antagonists in this study.Sympatholytin preferentially blocked postsynaptic alpha receptors.

General Description

N-(2-Chloroethyl)dibenzylamine hydrochloride is also referred as dibenamine. Mechanism of protection against carbon tetrachloride-induced hepatotoxicity produced by pretreatment with [N-(2-chloroethyl) dibenzylamine] hydrochloride has been investigated. It is a powerful adrenergic blocking agent, is known to modify the pharmacological effects of epinephrine.

Upstream product

• 100-39-0 benzyl bromide 
• 101-06-4 N,N-dibenzyl-2-aminoethanol 

Downstream Products

• 103042-67-7 1-(2-dibenzylamino-ethyl)-4-phenyl-piperazine 
• 31060-82-9 bis-(2-dibenzylamino-ethyl)-disulfide 
• 55097-20-6 2-Amino-2'-dibenzylaminodiethyl Sulfid 
• 84199-02-0 N₁,N₁-dibenzyl-N₂-methylethane-1,2-diamine 
• 758640-21-0 N-Benzylaniline 
• 118107-85-0 N-Benzyl-N'-phenyl-1,2-diaminoethane hydrochloride 
• 53197-73-2 2,7-Bis-(2-dibenzylamino-ethoxy)-fluoren-9-one 
• 152193-84-5 methyl N-(2-dibenzylaminoethyl)indole-2-carboxylate 
• 103280-08-6 benzenesulfonic acid-(2-dibenzylamino-ethyl ester); benzenesulfonate 
• 884850-52-6 6,7-methylenedioxyquinoline-4-carboxylic acid N-[2-(N,N-dibenzylamino)ethyl]-N-(2-iodo-4,5-dimethoxyphenyl)amide 

Relevant articles and documents

Preparation method of amino polyethylene glycol propionic acid

The invention relates to the field of organic synthesis, in particular to a preparation method of amino polyethylene glycol propionic acid. The preparation method comprises the steps that catalytic hydrogenation is carried out on dibenzyl amino polyethylene glycol tert-butyl propionate shown in formula I-2 to obtain amino polyethylene glycol tert-butyl propionate shown in formula I-3; (2) the amino polyethylene glycol tert-butyl propionate shown in formula I-3 is hydrolyzed under the acidic condition to obtain amino polyethylene glycol propionic acid shown in formula I. The preparation methodof the amino polyethylene glycol propionic acid has the advantages that the defects in the prior art that the yield is low, the dangerousness is high, and the enlargement of production is difficult are overcome, the reaction conditions are mild, the operation is simple, an intermediate does not to be purified, the next reaction can be directly carried out, the whole yield reaches up to 87-92%, thepurity of end products reaches up to 97-99.5%, and a safe and efficient synthetic route is provided for the preparation of amino polyethylene glycol propionic acid.