550-97-0Relevant articles and documents
Synthesis of salicylates from anionically activated aromatic trifluoromethyl group
Lin, Chuankai,Liu, Jin-Biao,Wang, Ruixiang,Xie, Huilin
supporting information, (2021/12/22)
An efficient approach to salicylates via a novel transformation of anionically activated aromatic trifluoromethyl group is described. Anionically activated trifluoromethyl group can react with phenols/alcohols under alkaline conditions to afford aryl/alkyl salicylates in high yields. Mechanism studies indicate that the carbonyl oxygen atom of ester is from the H2O in the solvent.
A photoredox-neutral Smiles rearrangement of 2-aryloxybenzoic acids
Gonzalez-Gomez, Jose C.,Ramirez, Nieves P.,Lana-Villarreal, Teresa,Bonete, Pedro
, p. 9680 - 9684 (2017/11/30)
We report on the use of visible light photoredox catalysis for the radical Smiles rearrangement of 2-aryloxybenzoic acids to obtain aryl salicylates. The method is free of noble metals and operationally simple and the reaction can be run under mild batch or flow conditions. Being a redox neutral process, no stoichiometric oxidants or reductants are needed.
Acylation of Phenols with Salicylic Acid Using Polyphosphoric Acid
Kamat, S. P.,Paknikar, S. K.
, p. 773 - 774 (2007/10/02)
Acylation of 2-naphthol (2), 1-naphthol (6) and resorcinol (11) with salicylic acid (1) in the presence of PPA affords salicylate esters (4, 7, 13 and 14), 1,2-benzoxanthone (5), 3,4-benzoxanthone (8), 3-hydroxyxanthone (12), 2-salicoyl-1-naphthol (9) and 11-hydroxy-12H-benzoxanthen-12-one (10).Compounds (4, 5, 7, 8, 12, 13 and 14) are identical with those obtained by heating a mixture of phenyl salicylate (3) and phenols (2, 6 and 11).